SCHEMBL320253

SCHEMBL320253

O=C(c1ccccc1)c1ccc(C[N+]2(Cc3ccc(C(=O)c4ccccc4)cc3)CCOCC2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.49
MAPT P10636 3/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
ALDH1A1 P00352 7/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
SRD5A2 P31213 1/20 0.43
SMN1; SMN2 Q16637 6/20 0.42
NPC1 O15118 4/20 0.42
RAB9A P51151 3/20 0.42
TP53 P04637 2/20 0.42
ALOX15 P16050 2/20 0.42
TSHR P16473 2/20 0.42
MAPK1 P28482 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
LMNA P02545 1/20 0.41
STAT1 P42224 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL232722 0.98 HPGD (0.48) HPGDMAPTCYP1A2CYP2C9NPSR1
SCHEMBL486989 0.89 ALDH1A1 (0.52) HPGDMAPTALDH1A1MEN1KMT2A
Bromide SCHEMBL231360 0.87 ALDH1A1 (0.50) HPGDMAPTALDH1A1MEN1KMT2A
SCHEMBL326805 0.76 ALDH1A1 (0.48) HPGDMAPTALDH1A1KMT2ASRD5A2
Benzophenone SCHEMBL9306548 0.75 ALDH1A1 (0.70) HPGDMAPTNPSR1ALDH1A1MEN1
SCHEMBL14700245 0.74 CYP2C9 (0.39) CYP1A2CYP2C9NPSR1ALDH1A1MEN1
Bromide SCHEMBL232885 0.74 ALDH1A1 (0.47) HPGDMAPTALDH1A1KMT2ASRD5A2
SCHEMBL4626526 0.73 HPGD (0.54) HPGDMAPTCYP1A2CYP2C9NPSR1
SCHEMBL28529627 0.72 HIF1A (0.68) HPGDMAPTALDH1A1KMT2ASMN1; SMN2
Benzophenone SCHEMBL9305504 0.72 ALDH1A1 (0.64) HPGDMAPTNPSR1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1503813-B1 SILANE COATING COMPOSITION SURMODICS INC (US) 2007-05-30 EP claimed
EP-1594623-B1 GRAFTING APPARTUS AND METHOD OF USING SURMODICS INC (US) 2007-04-11 EP claimed
EP-1503813-A1 SILANE COATING COMPOSITION SurModics, Inc. (US) 2005-02-09 EP claimed
US-6706408-B2 Silane coating composition SURMODICS, INC. 2004-03-16 US claimed
WO-2003097117-A1 SILANE COATING COMPOSITION SURMODICS, INC. (US) 2003-11-27 WO claimed
US-20030215649-A1 First coating layer of a silane compound, a hydrolysis reaction product of the silane compound or a polymeric silane compound, or mixture (free of sulfide group), a second layer of a polymer and a photoactivable crosslinker SURMODICS, INC. 2003-11-20 US claimed
WO-2026090506-A1 MEDICAL DEVICE COATINGS AND METHODS SURMODICS, INC. (US) 2026-04-30 WO disclosed
US-20260108663-A1 LOW PARTICULATE LUBRICIOUS COATING WITH VINYL PYRROLIDONE AND ACIDIC POLYMER-CONTAINING LAYERS SURMODICS INC (US) 2026-04-23 US disclosed
US-20260098225-A1 POLYACRYLIC ACID CONTAINING LUBRICIOUS COATINGS FOR MEDICAL DEVICES WITH ENHANCED PROPERTIES SURMODICS INC (US) 2026-04-09 US disclosed
US-12472288-B2 Lubricious coating for medical device SURMODICS, INC. (US) 2025-11-18 US disclosed
EP-4646241-A1 LUBRICIOUS COATINGS FOR MEDICAL DEVICES WITH ENHANCED DURABILITY SurModics, Inc. (US) 2025-11-12 EP disclosed
US-12441951-B2 Polyacrylic acid containing lubricious coatings for medical devices with enhanced properties SURMODICS, INC. (US) 2025-10-14 US disclosed
EP-4615530-A1 POLYACRYLIC ACID CONTAINING LUBRICIOUS COATINGS FOR MEDICAL DEVICES WITH ENHANCED PROPERTIES SurModics, Inc. (US) 2025-09-17 EP disclosed
WO-2006130776-A2 HYDROPHILIC POLYMERIC COATINGS FOR MEDICAL ARTICLES SURMODICS, INC. (US) 2006-12-07 WO disclosed
US-20060210816-A1 Compliant polymeric coatings for insertable medical articles BANK OF MONTREAL, AS COLLATERAL AGENT 2006-09-21 US disclosed
WO-2006099470-A2 COMPLIANT POLYMERIC COATINGS FOR INSERTABLE MEDICAL ARTICLES SURMODICS, INC. (US) 2006-09-21 WO disclosed
EP-1503813-A1 SILANE COATING COMPOSITION SurModics, Inc. (US) 2005-02-09 EP disclosed
US-6706408-B2 Silane coating composition SURMODICS, INC. 2004-03-16 US disclosed
WO-2003097117-A1 SILANE COATING COMPOSITION SURMODICS, INC. (US) 2003-11-27 WO disclosed
US-20030215649-A1 First coating layer of a silane compound, a hydrolysis reaction product of the silane compound or a polymeric silane compound, or mixture (free of sulfide group), a second layer of a polymer and a photoactivable crosslinker SURMODICS, INC. 2003-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260098225-A1 POLYACRYLIC ACID CONTAINING LUBRICIOUS COATINGS FOR MEDICAL DEVICES WITH ENHANCED PROPERTIES CUTA, EED, SELP HPGD 1192/4885MAPT 1717/4885CYP1A2 995/4885
US-20260108663-A1 LOW PARTICULATE LUBRICIOUS COATING WITH VINYL PYRROLIDONE AND ACIDIC POLYMER-CONTAINING LAYERS VCL, RAD54L, SELP HPGD 2251/4885MAPT 1438/4885CYP1A2 966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.