Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4627339 | 0.76 | CRHR1 (0.33) | CRHR1 | |
| SCHEMBL2070175 | 0.70 | LTB4R (0.34) | CRHR1IRAK4 | |
| SCHEMBL2072180 | 0.70 | HTR7 (0.37) | CRHR1 | |
| SCHEMBL31458627 | 0.70 | HTR7 (0.37) | CRHR1 | |
| SCHEMBL4628888 | 0.69 | HTR7 (0.36) | CRHR1 | |
| SCHEMBL4627833 | 0.65 | LTB4R (0.34) | — | |
| SCHEMBL4835739 | 0.65 | IRAK4 (0.40) | IRAK4 | |
| SCHEMBL4835904 | 0.64 | IRAK4 (0.39) | IRAK4 | |
| SCHEMBL4840772 | 0.64 | IRAK4 (0.39) | IRAK4 | |
| SCHEMBL4837461 | 0.64 | IRAK4 (0.39) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732541-A4 | CYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL (JP) | 2008-03-05 | — | — | EP | disclosed |
| EP-1732541-A2 | CYCLIC COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005099688-A2 | CYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-10-27 | — | — | WO | disclosed |