Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.31 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.31 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2070175 | 0.93 | LTB4R (0.34) | CRHR1ALDH1A1MTORPMP22SMN1; SMN2 | |
| SCHEMBL2071082 | 0.83 | LTB4R (0.39) | ALDH1A1MTORPMP22SMN1; SMN2CYP3A4 | |
| SCHEMBL4627831 | 0.82 | LTB4R (0.33) | CRHR1ALDH1A1MTORPMP22SMN1; SMN2 | |
| SCHEMBL4626195 | 0.76 | LTB4R (0.35) | ALDH1A1MTORPMP22SMN1; SMN2CYP3A4 | |
| SCHEMBL4627342 | 0.76 | CRHR1 (0.32) | CRHR1 | |
| SCHEMBL31458627 | 0.75 | HTR7 (0.37) | CRHR1ALDH1A1MAPK1 | |
| SCHEMBL2072180 | 0.75 | HTR7 (0.37) | CRHR1ALDH1A1MAPK1 | |
| SCHEMBL4627833 | 0.74 | LTB4R (0.34) | ALDH1A1MTORPMP22SMN1; SMN2CYP3A4 | |
| SCHEMBL4628888 | 0.73 | HTR7 (0.36) | CRHR1ALDH1A1MAPK1 | |
| SCHEMBL2070847 | 0.71 | NOS1 (0.40) | CRHR1ALDH1A1SMN1; SMN2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732541-A4 | CYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL (JP) | 2008-03-05 | — | — | EP | disclosed |
| EP-1732541-A2 | CYCLIC COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005099688-A2 | CYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-10-27 | — | — | WO | disclosed |