Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4628323 | 0.80 | ADAM17 (0.36) | HTR2AKCNH2 | |
| SCHEMBL4628637 | 0.78 | ADRB2 (0.38) | DRD2HTR2AHTR2CKCNH2 | |
| SCHEMBL4824727 | 0.78 | ADRB2 (0.38) | DRD2HTR2AHTR2CKCNH2 | |
| SCHEMBL4628643 | 0.68 | ADRB2 (0.54) | DRD2HTR2AHTR2CKCNH2 | |
| SCHEMBL5183995 | 0.67 | HRH3 (0.31) | — | |
| SCHEMBL8402417 | 0.66 | COMT (0.38) | ALOX5APFEN1DRD2HTR2AHTR2C | |
| SCHEMBL5455607 | 0.66 | KDM4E (0.47) | — | |
| SCHEMBL4802684 | 0.64 | CA1 (0.48) | — | |
| SCHEMBL1016972 | 0.64 | CTSB (0.42) | ALOX5APFEN1HTR2A | |
| SCHEMBL9586368 | 0.62 | CA2 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556342-B1 | PHENETHANOLAMINE DERIVATIVE FOR THE TREATMENT OF RESPIRATORY DISEASES | GLAXO GROUP LTD (GB) | 2008-03-26 | — | — | EP | disclosed |