SCHEMBL4627558

SCHEMBL4627558

Nc1nc(OC(=O)NC(=O)C=NO)cs1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.33
GABRA5 P31644 1/20 0.33
GABRB2 P47870 1/20 0.33
ALDH1A1 P00352 5/20 0.32
MEN1 O00255 3/20 0.32
MAPT P10636 3/20 0.32
KMT2A Q03164 3/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
KDM4E B2RXH2 2/20 0.31
CYP1A2 P05177 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10401135 0.81 HSD17B10 (0.37) HSD17B10GABRA5GABRB2ALDH1A1MEN1
SCHEMBL8329867 0.81 HSD17B10 (0.37) HSD17B10GABRA5GABRB2ALDH1A1MEN1
SCHEMBL27328375 0.71 ALDH1A1 (0.38) HSD17B10GABRA5GABRB2ALDH1A1MEN1
SCHEMBL1417466 0.70 GABRA5 (0.47) HSD17B10GABRA5GABRB2ALDH1A1MEN1
SCHEMBL27851070 0.70 GABRA5 (0.43) HSD17B10GABRA5GABRB2ALDH1A1MEN1
SCHEMBL27622470 0.69 GABRA5 (0.40) HSD17B10GABRA5GABRB2ALDH1A1MEN1
SCHEMBL1000856 0.69 ALDH1A1 (0.44) HSD17B10GABRA5GABRB2ALDH1A1MEN1
SCHEMBL9055334 0.69 ALDH1A1 (0.36) HSD17B10GABRA5GABRB2ALDH1A1MEN1
SCHEMBL5298283 0.69 ALDH1A1 (0.36) HSD17B10GABRA5GABRB2ALDH1A1MEN1
Hydrochloric Acid SCHEMBL27328374 0.68 ALDH1A1 (0.38) HSD17B10GABRA5GABRB2ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1546154-A4 PROCESS FOR THE PREPARATION OF CEFDINIR RANBAXY LAB LTD (IN) 2008-03-26 EP disclosed
US-20060040915-A1 Process for the preparation of cefdinir RANBAXY LABORATORIES LIMITED (IN) 2006-02-23 US disclosed
EP-1546154-A1 PROCESS FOR THE PREPARATION OF CEFDINIR RANBAXY LABORATORIES, LTD. (IN) 2005-06-29 EP disclosed
WO-2003091261-A1 PROCESS FOR THE PREPARATION OF CEFDINIR RANBAXY LABORATORIES LIMITED (IN) 2003-11-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060040915-A1 Process for the preparation of cefdinir DCXR, C1R, PEPD HSD17B10 485/4885GABRA5 957/4885GABRB2 1604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.