Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4628820 | 1.00 | FFAR2 (0.44) | FFAR2RAB9APOLBALDH1A1L3MBTL1 | |
| SCHEMBL6666845 | 0.76 | ATM (0.40) | FFAR2RAB9APOLBALDH1A1L3MBTL1 | |
| SCHEMBL19489069 | 0.70 | POLB (0.38) | FFAR2RAB9APOLBALDH1A1L3MBTL1 | |
| SCHEMBL18638766 | 0.70 | FFAR2 (0.57) | FFAR2RAB9APOLBALDH1A1L3MBTL1 | |
| SCHEMBL13101011 | 0.70 | CTSK (0.51) | FFAR2RAB9APOLBALDH1A1L3MBTL1 | |
| SCHEMBL18642522 | 0.69 | FDPS (0.58) | RAB9AALDH1A1ATMNPC1SMN1; SMN2 | |
| SCHEMBL18642520 | 0.69 | FDPS (0.58) | RAB9AALDH1A1ATMNPC1SMN1; SMN2 | |
| SCHEMBL3596299 | 0.68 | RAB9A (0.51) | RAB9APOLBALDH1A1L3MBTL1ATM | |
| SCHEMBL27348676 | 0.68 | RAB9A (0.38) | FFAR2RAB9APOLBALDH1A1TSHR | |
| SCHEMBL14555163 | 0.68 | KDM4C (0.46) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592801-A4 | TANDEM ANALYSES OF NONCOVALENTLY DRIVEN EFFECTORS FOR MODULATORY MAPPING OF ACTIVITIES OF PROTEIN SITES | ADVANCED PROTEOME THERAPEUTICS (US) | 2008-04-30 | — | — | EP | disclosed |
| EP-1592801-A2 | TANDEM ANALYSES OF NONCOVALENTLY DRIVEN EFFECTORS FOR MODULATORY MAPPING OF ACTIVITIES OF PROTEIN SITES | Advanced Proteome Therapeutics Inc. (US) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004066917-A2 | TANDEM ANALYSES OF NONCOVALENTLY DRIVEN EFFECTORS FOR MODULATORY MAPPING OF ACTIVITIES OF PROTEIN SITES | ADVANCED PROTEOME THERAPEUTICS, INC (US) | 2004-08-12 | — | — | WO | disclosed |