Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GRK2 | P25098 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147797 | 0.82 | KDM4E (0.55) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL3359441 | 0.79 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL146809 | 0.79 | ALDH1A1 (0.55) | PTGS2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3729672 | 0.79 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL14194615 | 0.79 | KDM4E (0.55) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL23619123 | 0.79 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL312571 | 0.79 | CYP1A2 (0.59) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL382956 | 0.78 | PTGS2 (0.48) | PTGS2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13990963 | 0.76 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL4628418 | 0.76 | PTGS2 (0.55) | PTGS2KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539155-B1 | STABLE CREAM PREPARATIONS OF PHENYL-PYRIDONE COMPOUNDS FOR TOPICAL APPLICATION | MEPHA AG (CH) | 2008-04-02 | — | — | EP | claimed |