Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6662170 | 0.82 | CYP19A1 (0.58) | KMT2AGAAHTTMEN1NPC1 | |
| SCHEMBL31561597 | 0.79 | CA2 (0.62) | KMT2ANPC1CA2CA1AKR1B1 | |
| SCHEMBL3237494 | 0.79 | CA2 (0.62) | KMT2ANPC1CA2CA1AKR1B1 | |
| SCHEMBL29520525 | 0.78 | CA2 (0.57) | KMT2ACA2CA1AKR1B1LMNA | |
| SCHEMBL4629441 | 0.77 | CA2 (0.57) | POLBCA2CA1AKR1B1LMNA | |
| SCHEMBL9580710 | 0.77 | KMT2A (1.00) | KMT2AGAAHTTMEN1CA2 | |
| SCHEMBL3477247 | 0.76 | KMT2A (0.89) | KMT2AGAAHTTMEN1CA2 | |
| SCHEMBL28568569 | 0.75 | CA2 (0.71) | NPC1CA2CA1AKR1B1MAPT | |
| SCHEMBL8960439 | 0.74 | CA2 (0.56) | GAACA2CA1AKR1B1MAPT | |
| SCHEMBL670176 | 0.74 | CA2 (0.56) | KMT2AGAAMEN1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919896-A1 | AMINOARYL SULPHONAMIDE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS. | Suven Life Sciences Limited (IN) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007020652-A1 | AMINOARYL SULPHONAMIDE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS. | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |