Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3509742 | 0.83 | CPT1B (0.36) | CES2CES1HPGDCPT1BALDH1A1 | |
| SCHEMBL4260216 | 0.81 | HTT (0.39) | HPGDTAS1R3TAS1R1MAPTALDH1A1 | |
| SCHEMBL2654895 | 0.81 | TSHR (0.37) | HPGDTAS1R3TAS1R1CPT1BCA2 | |
| SCHEMBL13621657 | 0.80 | HPGD (0.37) | HPGDTAS1R3TAS1R1TDP1ALDH1A1 | |
| SCHEMBL14199325 | 0.78 | HPGD (0.37) | HPGDTAS1R3TAS1R1ALDH1A1MEN1 | |
| SCHEMBL2647108 | 0.78 | TAS1R3 (0.54) | CES2CES1TAS1R3TAS1R1CPT1B | |
| SCHEMBL1857913 | 0.76 | CA2 (0.43) | HPGDTAS1R3TAS1R1KMT2ACA2 | |
| SCHEMBL1107467 | 0.73 | CPT1B (0.47) | CES2CES1HPGDCPT1BALDH1A1 | |
| SCHEMBL10582008 | 0.72 | CES2 (0.70) | CES2CES1HPGDCPT1BTDP1 | |
| SCHEMBL13621539 | 0.71 | HPGD (0.36) | HPGDCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1921074-A1 | THIAZOLE DERIVATIVE | Astellas Pharma Inc. (JP) | 2008-05-14 | — | — | EP | disclosed |