Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | WRN | Q14191 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8682479 | 0.84 | MGLL (0.34) | CYP2C19PTGS1PTGS2KMT2AMGLL | |
| SCHEMBL4655509 | 0.84 | ALDH1A1 (0.33) | CYP2C19PTGS1PTGS2KMT2AMGLL | |
| SCHEMBL30487816 | 0.83 | ALDH1A1 (0.41) | CYP2C19KMT2AALDH1A1BLMLMNA | |
| SCHEMBL23854822 | 0.81 | PTGS1 (0.33) | CYP2C19PTGS1PTGS2KMT2AMGLL | |
| SCHEMBL20448437 | 0.80 | CYP2C19 (0.47) | CYP2C19TBXAS1KMT2AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL14765289 | 0.79 | CA12 (0.32) | PTGS1PTGS2MGLLFAAHLMNA | |
| SCHEMBL28712712 | 0.79 | CYP2C19 (0.30) | CYP2C19 | |
| SCHEMBL28600387 | 0.78 | ALDH1A1 (0.38) | CYP2C19PTGS1PTGS2ALDH1A1BLM | |
| SCHEMBL7847932 | 0.77 | CA12 (0.49) | CYP2C19KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL28613564 | 0.76 | CYP2C19 (0.52) | CYP2C19TBXAS1KMT2AALDH1A1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 527 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111246873-B | Optimized peptides for targeting human nerves and their use in image guided surgery, diagnosis and therapy delivery | 加利福尼亚大学董事会 | 2024-03-01 | — | — | CN | claimed |
| CN-110062767-B | Human antibodies, pharmaceutical compositions and methods | 台湾浩鼎生技股份有限公司 | 2023-07-11 | — | — | CN | claimed |
| WO-2023113243-A1 | MODIFIED OLIGONUCLEOTIDE-DRUG CONJUGATE AND USE THEREOF | 인터올리고 주식회사 | 2023-06-22 | — | — | WO | claimed |
| US-20230132568-A1 | ANTIBODY-ALK5 INHIBITOR CONJUGATES AND THEIR USES | SYNTHIS THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | US | claimed |
| US-20230090552-A1 | ALK5 INHIBITOR CONJUGATES AND USES THEREOF | SYNTHIS THERAPEUTICS, INC. (US) | 2023-03-23 | — | — | US | claimed |
| CN-115052663-A | ALK5 inhibitor conjugates and uses thereof | 辛瑟斯治疗股份有限公司 | 2022-09-13 | — | — | CN | claimed |
| CN-114929263-A | Intercellular adhesion molecule 1(ICAM1) antibody drug conjugates and uses thereof | 儿童医学中心公司 | 2022-08-19 | — | — | CN | claimed |
| US-20220249680-A1 | ANTIBODY-ALK5 INHIBITOR CONJUGATES AND THEIR USES | SYNTHIS THERAPEUTICS, INC. (US) | 2022-08-11 | — | — | US | claimed |
| EP-3986468-A1 | ANTIB0DY-ALK5 INHIBITOR CONJUGATES AND THEIR USES | Synthis Therapeutics, Inc. (US) | 2022-04-27 | — | — | EP | claimed |
| CN-114269388-A | antibody-ALK 5 inhibitor conjugates and uses thereof | 辛瑟斯治疗股份有限公司 | 2022-04-01 | — | — | CN | claimed |
| EP-2922875-B1 | ANTI-CEACAM5 ANTIBODIES AND USES THEREOF | SANOFI SA (FR) | 2017-03-15 | — | — | EP | claimed |
| EP-2140263-B1 | HAPTEN COMPOUNDS AND COMPOSITIONS AND USES THEREOF | UNIV ARKANSAS (US) | 2017-01-04 | — | — | EP | claimed |
| US-8853146-B2 | Hapten compounds and compositions and uses thereof | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2014-10-07 | — | — | US | claimed |
| US-20100143391-A1 | HAPTEN COMPOUNDS AND COMPOSITIONS AND USES THEREOF | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2010-06-10 | — | — | US | claimed |
| EP-2140263-A1 | HAPTEN COMPOUNDS AND COMPOSITIONS AND USES THEREOF | Board of Trustees of the University of Arkansas (US) | 2010-01-06 | — | — | EP | claimed |
| WO-2008131216-A1 | HAPTEN COMPOUNDS AND COMPOSITIONS AND USES THEREOF | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2008-10-30 | — | — | WO | claimed |
| EP-1472351-B1 | AMINO ACID SEQUENCES CAPABLE OF FACILITATING PENETRATION ACROSS A BIOLOGICAL BARRIER | YISSUM RES DEV CO (IL) | 2007-06-20 | — | — | EP | claimed |
| EP-1689846-A2 | METHOD OF TARGETING SPECIFIC CELL POPULATIONS USING CELL-BINDING AGENT MAYTANSINOID CONJUGATES LINKED VIA A NON-CLEAVABLE LINKER, SAID CONJUGATES, AND METHODS OF MAKING SAID CONJUGATES | Immunogen, Inc. (US) | 2006-08-16 | — | — | EP | claimed |
| WO-2005037992-A2 | METHOD OF TARGETING SPECIFIC CELL POPULATIONS USING CELL-BINDING AGENT MAYTANSINOID CONJUGATES LINKED VIA A NON-CLEAVABLE LINKER, SAID CONJUGATES, AND METHODS OF MAKING SAID CONJUGATES | IMMUNOGEN, INC. (US) | 2005-04-28 | — | — | WO | claimed |
| WO-1997040061-A1 | ESTROGEN-PURINE BASE, ESTROGEN-MERCAPTURATE ADDUCTS, AND FLUORESCENT PROBES AND MONOCLONAL ANTIBODIES THEREOF | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1997-10-30 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220249680-A1 | ANTIBODY-ALK5 INHIBITOR CONJUGATES AND THEIR USES | ALK, ALKBH5, ALKBH3 | CYP2C19 3531/4885PTGS1 4761/4885PTGS2 4731/4885 |
| US-20230090552-A1 | ALK5 INHIBITOR CONJUGATES AND USES THEREOF | ALK, ALKBH5, ALKBH3 | CYP2C19 3565/4885PTGS1 3620/4885PTGS2 3886/4885 |
| US-20230132568-A1 | ANTIBODY-ALK5 INHIBITOR CONJUGATES AND THEIR USES | ALK, ALKBH5, ALKBH3 | CYP2C19 3531/4885PTGS1 4761/4885PTGS2 4731/4885 |
| US-20100143391-A1 | HAPTEN COMPOUNDS AND COMPOSITIONS AND USES THEREOF | DDT, TAAR5, MLLT1 | CYP2C19 572/4885PTGS1 3348/4885PTGS2 3028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.