SCHEMBL4629626

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18554543	0.88	PDE5A (0.46)	GRIN2DGRIN3BGRIA1GRIA2GRIA3
	SCHEMBL29532334	0.83	KDM4E (0.56)	B3GNT2KDM4EALDH1A1HPGDMEN1
	SCHEMBL24317932	0.83	KDM4E (0.56)	B3GNT2KDM4EALDH1A1HPGDMEN1
	SCHEMBL8890567	0.82	HDAC1 (0.47)	GRIN2DGRIN3BGRIA1GRIA2GRIA3
	SCHEMBL640508	0.82	CBX7 (0.58)	B3GNT2GRIN2DGRIN3BGRIA1GRIA2
	SCHEMBL641660	0.82	B3GNT2 (0.47)	B3GNT2GRIN2DGRIN3BGRIA1GRIA2
	SCHEMBL30289018	0.80	KDM4E (0.42)	B3GNT2AKT2CLK2DYRK1ACLK4
	SCHEMBL22191016	0.80	CYP1A2 (0.60)	B3GNT2AKT2CLK2DYRK1ACLK4
	SCHEMBL6540522	0.79	PGR (0.61)	AKT2CLK2DYRK1ACLK4KDM4E
	SCHEMBL2255490	0.78	MEN1 (0.62)	KDM4EALDH1A1HPGDAPEX1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.