Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16621838 | 0.81 | CYP2C9 (0.35) | ALDH1A1DPP4CYP2C9 | |
| SCHEMBL11892723 | 0.76 | ALDH1A1 (0.33) | ALDH1A1DPP4 | |
| SCHEMBL5478015 | 0.76 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL224792 | 0.75 | ALDH1A1 (0.35) | ALDH1A1RAB9AHTTNPC1LMNA | |
| SCHEMBL17472073 | 0.73 | DPP4 (0.31) | DPP4 | |
| SCHEMBL18312207 | 0.71 | DPP4 (0.33) | DPP4 | |
| SCHEMBL6297662 | 0.68 | ALDH1A1 (0.36) | ALDH1A1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL8747226 | 0.68 | ZDHHC20 (0.35) | ALDH1A1DPP4 | |
| SCHEMBL16083147 | 0.65 | — | — | |
| SCHEMBL9636884 | 0.64 | HMGCR (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332459-B2 | Benzimidazole derivatives and their uses | TEIJIN PHARMA LIMITED (JP) | 2022-05-17 | — | — | US | disclosed |
| US-20200308145-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USES | AMGEN INC. (US) | 2020-10-01 | — | — | US | disclosed |
| US-20080227635-A1 | Dicyano Alkanoic Acid Amides for Combating Animal Pests | BASF AKTIENGESELLSCHAFT (DE) | 2008-09-18 | — | — | US | disclosed |
| EP-1916895-A1 | DICYANO ALKANOIC ACID AMIDES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007014899-A1 | DICYANO ALKANOIC ACID AMIDES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2007-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200308145-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USES | TRPC6, TRPV6, TRPM6 | ALDH1A1 1564/4885RAB9A 3271/4885HTT 2535/4885 |
| US-20080227635-A1 | Dicyano Alkanoic Acid Amides for Combating Animal Pests | CBR3, CBR1, C3AR1 | ALDH1A1 1759/4885RAB9A 605/4885HTT 2385/4885 |
| US-11332459-B2 | Benzimidazole derivatives and their uses | TRPC6, TRPV6, TRPM6 | ALDH1A1 1564/4885RAB9A 3271/4885HTT 2535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.