SCHEMBL4629783

SCHEMBL4629783

NCCCc1cccc(P)c1CCCN

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MPO P05164 2/20 0.39
SLC6A4 P31645 2/20 0.39
TAAR1 Q96RJ0 8/20 0.38
TLR8 Q9NR97 4/20 0.36
MAOA P21397 1/20 0.34
CYP2A6 P11509 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28402775 0.87 TAAR1 (0.43) MPOSLC6A4TAAR1TLR8MAOA
SCHEMBL8835942 0.83 TAAR1 (0.47) MPOSLC6A4TAAR1CYP2A6
SCHEMBL8589255 0.80 MAOA (0.48) MPOSLC6A4TAAR1TLR8MAOA
SCHEMBL1952602 0.79 TLR8 (0.39) MPOSLC6A4TAAR1TLR8MAOA
SCHEMBL5596861 0.79 POLB (0.37)
SCHEMBL301548 0.79 LIPG (0.40) TLR8
SCHEMBL5268701 0.79
SCHEMBL5729888 0.78 LIPG (0.47)
Hydrochloric Acid SCHEMBL9110884 0.78 TLR8 (0.38) MPOSLC6A4TAAR1TLR8MAOA
SCHEMBL8017596 0.77 PNMT (0.40) MPOSLC6A4TAAR1TLR8MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1838746-B1 WATER- AND OIL-REPELLENT FLUOROURETHANES AND FLUOROUREAS 3M INNOVATIVE PROPERTIES CO (US) 2012-06-06 EP claimed
US-7268197-B2 Water- and oil-repellent fluorourethanes and fluoroureas 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-09-11 US claimed
EP-1838746-B1 WATER- AND OIL-REPELLENT FLUOROURETHANES AND FLUOROUREAS 3M INNOVATIVE PROPERTIES CO (US) 2012-06-06 EP disclosed
EP-1917285-A1 REPELLENT MATERIALS 3M Innovative Properties Company (US) 2008-05-07 EP disclosed
EP-1838746-A1 WATER- AND OIL-REPELLENT FLUOROURETHANES AND FLUOROUREAS 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-10-03 EP disclosed
US-7268197-B2 Water- and oil-repellent fluorourethanes and fluoroureas 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-09-11 US disclosed
WO-2007019263-A1 REPELLENT MATERIALS 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-02-15 WO disclosed
US-20070032627-A1 Repellent materials 3M INNOVATIVE PROPERTIES COMPANY 2007-02-08 US disclosed
WO-2006071498-A1 WATER- AND OIL-REPELLENT FLUOROURETHANES AND FLUOROUREAS 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-07-06 WO disclosed
US-20060142474-A1 WATER- AND OIL-REPELLENT FLUOROURETHANES AND FLUOROUREAS 3M INNOVATIVE PROPERTIES COMPANY 2006-06-29 US disclosed
US-20060142530-A1 Water- and oil-repellent fluorourethanes and fluoroureas 3M INNOVATIVE PROPERTIES COMPANY 2006-06-29 US disclosed
EP-0046331-A2 Nickel ylides GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-02-24 EP disclosed
EP-0046329-A1 Process for the oligomerization of ethylene GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-02-24 EP disclosed
EP-0046330-A2 Process for the preparation of nickel ylides containing sulfonated group V ligands GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-02-24 EP disclosed
EP-0046328-A1 Process for the oligomerization of ethylene in methanol GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-02-24 EP disclosed
EP-0046332-A2 Process for the preparation of nickel ylides containing ylide ligands with a sulfonated group V component GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-02-24 EP disclosed
US-4310716-A NICKEL YLIDE CATALYST GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-01-12 US disclosed
US-4301318-A OBTAINED BY REACTING ETHYLENE USING A NICKEL YLIDE CATALYST; SOLVENT EXTRACTION OF CATALYST USING AMMONIUM HYDROXIDE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1981-11-17 US disclosed
US-4293727-A CATALYSIS WITH NICKEL YLIDE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1981-10-06 US disclosed
US-4293502-A CATALYST FOR OLIGOMERIZATION OF ETHYLENE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1981-10-06 US disclosed