Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.39 |
| ▸ | MPO | P05164 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9110884 | 0.98 | TLR8 (0.38) | TLR8MPOSLC6A4TAAR1CYP3A4 | |
| SCHEMBL28402775 | 0.87 | TAAR1 (0.43) | TLR8MPOSLC6A4TAAR1MAOA | |
| SCHEMBL9843984 | 0.82 | CYP3A4 (0.36) | SLC6A4CYP3A4TSHRPIK3CA | |
| SCHEMBL140512 | 0.82 | SKP2 (0.43) | TLR8CYP3A4TSHRPIK3CA | |
| SCHEMBL8589255 | 0.80 | MAOA (0.48) | TLR8MPOSLC6A4TAAR1MAOA | |
| SCHEMBL5928190 | 0.80 | SIGMAR1 (0.43) | TLR8MPOSLC6A4TAAR1CYP3A4 | |
| SCHEMBL30498596 | 0.80 | SIGMAR1 (0.43) | TLR8MPOSLC6A4TAAR1CYP3A4 | |
| SCHEMBL4629783 | 0.79 | MPO (0.39) | TLR8MPOSLC6A4TAAR1MAOA | |
| SCHEMBL119639 | 0.79 | LIPG (0.49) | TLR8 | |
| SCHEMBL4308876 | 0.79 | LIPG (0.49) | TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2332998-B1 | Solvent free aqueous polyurethane dispersions and methods of making and using the same | VERSUM MAT US LLC (US) | 2018-09-26 | — | — | EP | disclosed |
| US-9617453-B2 | Solvent free aqueous polyurethane dispersions and methods of making and using the same | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2017-04-11 | — | — | US | disclosed |
| US-20110306724-A1 | Solvent Free Aqueous Polyurethane Dispersions and Methods of Making and Using the Same | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2011-12-15 | — | — | US | disclosed |
| EP-2332998-A1 | Solvent free aqueous polyurethane dispersions and methods of making and using the same | Air Products and Chemicals, Inc. (US) | 2011-06-15 | — | — | EP | disclosed |
| US-20020055602-A1 | Aromatic polyisocyanates blocked by pyrazole or pyrazole derivatives and the preparation and use thereof | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-09 | — | — | US | disclosed |
| EP-1184400-A1 | Aromatic polyisocyanates blocked with pyrazole or pyrazole derivatives, process for their preparation and their use | BAYER AG (DE) | 2002-03-06 | — | — | EP | disclosed |
| US-5693737-A | POLYETHERURETHANES FOR PREPARING CREASE-RESISTANT TEXTILES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-02 | — | — | US | disclosed |
| US-5607482-A | BLOCKED POLYISOCYANATE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |
| EP-0449041-B1 | Blends of cellulose and synthetic polymers, manufacture and uses thereof | WOLFF WALSRODE AG (DE) | 1996-09-11 | — | — | EP | disclosed |
| EP-0537578-B1 | Blocked polyisocyanate dispersable in water, process for its preparation and its use | BAYER AG (DE) | 1996-07-31 | — | — | EP | disclosed |
| US-4324716-A | -POLYURETHANE FOAMS | BAYER AKTIENGESELLSCHAFT (DE) | 1982-04-13 | — | — | US | disclosed |
| US-4315859-A | STABILIZES PROVIDE PHOTSTABILITY OXIDATION RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1982-02-16 | — | — | US | disclosed |
| US-4310448-A | POLYETHER OR POLYESTER DISPERSANTS FOR POLYURETHANES OR POLUREAS | BAYER AKTIENGESELLSCHAFT (DE) | 1982-01-12 | — | — | US | disclosed |
| US-4305858-A | Process for the preparation of stable ionic dispersions of polyisocyanate-polyaddition products in hydroxyl containing compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1981-12-15 | — | — | US | disclosed |
| EP-0013665-A1 | Polymeric polyamino 1,3,5-triazines containing at least one polyalkylpiperidine group, their preparation, their use in stabilizing an organic material and the material stabilized therewith | CIBA-GEIGY AG (CH) | 1980-07-23 | — | — | EP | disclosed |
| US-4184990-A | Process for the preparation of stable dispersions of polyisocyanate-polyaddition products in a hydroxyl containing compound as dispersing agent | BAYER AKTIENGESELLSCHAFT (DE) | 1980-01-22 | — | — | US | disclosed |
| US-4147680-A | Production of polyurethane resins using as active hydrogen material a stable dispersion of ionic polyisocyanate-polyaddition products in hydroxyl containing compounds as a dispersing agent | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-03 | — | — | US | disclosed |
| US-4092275-A | Polyurethane resins prepared from active hydrogen containing material which is a dispersion of polyisocyanate-polyaddition products in hydroxyl containing compounds as dispersing agents | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-30 | — | — | US | disclosed |
| US-4083847-A | Transiently water-soluble disperse mono-azo dyes containing a diamino-methylene-carbacyl group | CIBA-GEIGY CORPORATION (US) | 1978-04-11 | — | — | US | disclosed |
| US-3970601-A | COATINGS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-20 | — | — | US | disclosed |