Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.58 |
| ▸ | CNR1 | P21554 | 5/20 | 0.52 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.44 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.43 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7245923 | 0.85 | CA2 (0.65) | CA2CNR1BCAT1MAPTALOX12 | |
| SCHEMBL4629425 | 0.84 | FLT3 (0.38) | CA2CNR1ALDH1A1KDM4EFLT3 | |
| SCHEMBL4630016 | 0.81 | CA2 (0.46) | CA2CNR1BCAT1ALDH1A1KDM4E | |
| SCHEMBL11015647 | 0.75 | CA2 (0.65) | CA2CNR1BCAT1MAPTALOX12 | |
| SCHEMBL10345372 | 0.74 | CA2 (1.00) | CA2CNR1MAPTCA12CA1 | |
| SCHEMBL11317837 | 0.72 | SMN1; SMN2 (0.56) | CA2MAPTCA12CA1ALDH1A1 | |
| SCHEMBL28794298 | 0.72 | CA2 (0.49) | CA2CNR1BCAT1MAPTPDGFRB | |
| SCHEMBL2270572 | 0.71 | HTR6 (0.71) | POLBMEN1KMT2A | |
| SCHEMBL4451325 | 0.69 | AKR1B1 (0.68) | CA2CNR1ALDH1A1POLBAXL | |
| SCHEMBL23936761 | 0.69 | AXL (0.61) | CA2MAPTALDH1A1POLBAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919896-A1 | AMINOARYL SULPHONAMIDE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS. | Suven Life Sciences Limited (IN) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007020652-A1 | AMINOARYL SULPHONAMIDE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS. | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |