Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 3/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4630184 | 0.84 | CA2 (0.58) | FLT3KDM4EALDH1A1HSD17B10CNR1 | |
| SCHEMBL27867018 | 0.82 | KDM4E (0.47) | FLT3AKR1B1KDM4EPDPK1ALDH1A1 | |
| SCHEMBL3630726 | 0.82 | FLT3 (0.48) | FLT3AKR1B1KDM4EPDPK1ALDH1A1 | |
| SCHEMBL4629545 | 0.81 | VCP (0.47) | KDM4E | |
| Hydrochloric Acid SCHEMBL4628914 | 0.80 | VCP (0.46) | KDM4E | |
| SCHEMBL4724711 | 0.78 | VCP (0.41) | — | |
| SCHEMBL4762974 | 0.78 | VCP (0.41) | — | |
| SCHEMBL3633471 | 0.77 | MEN1 (0.44) | AKR1B1KDM4EPDPK1ALDH1A1LMNA | |
| SCHEMBL4762174 | 0.76 | MAPT (0.43) | KDM4EALDH1A1TDP1 | |
| SCHEMBL11317837 | 0.73 | SMN1; SMN2 (0.56) | KDM4EALDH1A1LMNAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919896-A1 | AMINOARYL SULPHONAMIDE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS. | Suven Life Sciences Limited (IN) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007020652-A1 | AMINOARYL SULPHONAMIDE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS. | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |