Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29527139 | 0.84 | HSD17B10 (0.41) | HSD17B10L3MBTL1CYP11B1CYP11B2PIP4K2A | |
| SCHEMBL29066214 | 0.84 | HSD17B10 (0.41) | HSD17B10L3MBTL1CYP11B1CYP11B2PIP4K2A | |
| SCHEMBL29066236 | 0.84 | HSD17B10 (0.44) | HSD17B10L3MBTL1CYP11B1CYP11B2PIP4K2A | |
| SCHEMBL29527271 | 0.84 | HSD17B10 (0.44) | HSD17B10L3MBTL1CYP11B1CYP11B2PIP4K2A | |
| SCHEMBL24802440 | 0.77 | CYP17A1 (0.37) | CYP11B2 | |
| SCHEMBL46329 | 0.77 | SMN1; SMN2 (0.40) | HSD17B10L3MBTL1GAACYP11B1CYP11B2 | |
| SCHEMBL29066185 | 0.75 | KDM4E (0.40) | HSD17B10L3MBTL1PIP4K2ASMN1; SMN2NPC1 | |
| SCHEMBL29527699 | 0.75 | FFAR1 (0.40) | HSD17B10CYP11B1CYP11B2PIP4K2AFFAR1 | |
| SCHEMBL29066188 | 0.75 | FFAR1 (0.40) | HSD17B10CYP11B1CYP11B2PIP4K2AFFAR1 | |
| SCHEMBL29526566 | 0.75 | HSD17B10 (0.34) | HSD17B10CYP11B1CYP11B2PIP4K2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151436-A2 | NOVEL COMPOUNDS, METHOD FOR USE THEM AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | EUROSCREEN S.A. (BE) | 2011-12-08 | — | — | WO | disclosed |