Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.42 |
| ▸ | DAO | P14920 | 2/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | AGXT | P21549 | 2/20 | 0.32 |
| ▸ | DBH | P09172 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5976699 | 0.84 | IDO1 (0.39) | IDO1DAOCYP17A1CYP21A2CYP11B1 | |
| SCHEMBL16956937 | 0.84 | CA12 (0.50) | IDO1CA12CA1CA9TAAR1 | |
| SCHEMBL13822389 | 0.84 | DAO (0.36) | IDO1DAOCYP17A1CYP21A2CYP11B1 | |
| SCHEMBL16954621 | 0.84 | MAOB (0.33) | IDO1DAOCYP17A1CYP21A2CYP11B1 | |
| SCHEMBL16953464 | 0.84 | RAPGEF4 (0.35) | IDO1DAOCYP17A1CYP21A2CYP11B1 | |
| SCHEMBL5975748 | 0.82 | IDO1 (0.38) | IDO1DAOCYP17A1CYP21A2CYP11B1 | |
| SCHEMBL16105495 | 0.82 | IDO1 (0.50) | IDO1DAOCYP17A1CYP21A2CYP11B1 | |
| SCHEMBL27959417 | 0.80 | IDO1 (0.37) | IDO1DAOCYP17A1CYP21A2CYP11B1 | |
| SCHEMBL16959257 | 0.80 | IDO1 (0.38) | IDO1DAOTAAR1 | |
| SCHEMBL148109 | 0.77 | IDO1 (0.46) | IDO1DAOCA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110358445-B | Composition for forming water-repellent film and water-repellent film | 信越化学工业株式会社 | 2022-06-17 | — | — | CN | disclosed |
| US-11118072-B2 | Water repellent film-forming composition and water repellent film | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2021-09-14 | — | — | US | disclosed |
| EP-3553121-B1 | WATER REPELLENT FILM-FORMING COMPOSITION AND WATER REPELLENT FILM | SHINETSU CHEMICAL CO (JP) | 2021-06-09 | — | — | EP | disclosed |
| CN-110358445-A | Water repellent film, which is formed, uses composition and water repellent film | 信越化学工业株式会社 | 2019-10-22 | — | — | CN | disclosed |
| US-20190315972-A1 | WATER REPELLENT FILM-FORMING COMPOSITION AND WATER REPELLENT FILM | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2019-10-17 | — | — | US | disclosed |
| EP-3553121-A1 | WATER REPELLENT FILM-FORMING COMPOSITION AND WATER REPELLENT FILM | Shin-Etsu Chemical Co., Ltd. (JP) | 2019-10-16 | — | — | EP | disclosed |
| CN-107141313-A | Transparent oxide electrode and its production method that surface modifier, surface for transparent oxide electrode are modified | 信越化学工业株式会社 | 2017-09-08 | — | — | CN | disclosed |
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| CN-103848859-A | Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing same | SHINETSU CHEMICAL CO | 2014-06-11 | — | — | CN | disclosed |
| EP-1919907-A2 | HETEROCYCLIC COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007026959-A2 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | WO | disclosed |
| US-7015345-B2 | Propionic acid derivatives | ASAHI KASEI PHARMA CORPORATION (JP) | 2006-03-21 | — | — | US | disclosed |
| EP-1484316-A1 | NOVEL PROPIONIC ACID DERIVATIVE | Asahi Kasei Pharma Corporation (JP) | 2004-12-08 | — | — | EP | disclosed |
| US-20040072690-A1 | Novel propionic acid derivatives | ASAHI KASEI PHARMA CORPORATION (JP) | 2004-04-15 | — | — | US | disclosed |
| US-6265434-B1 | ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |
| EP-0190817-B1 | DOPAMINE-BETA-HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1990-09-05 | — | — | EP | disclosed |
| US-4857540-A | 1-SUBSTITUTED-2-MERCAPTO-(OR AMINOMETHYL-)BENZAMIDAZOLE COMPOUNDS | SMITHKLINE BECKMAN CORPORATION (US) | 1989-08-15 | — | — | US | disclosed |
| US-4728741-A | DOPAMINE BETA-HYDROXYLASE INHIBITOR | SMITHKLINE BECKMAN CORPORATION (US) | 1988-03-01 | — | — | US | disclosed |
| EP-0190817-A1 | Dopamine-beta-hydroxylase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1986-08-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072690-A1 | Novel propionic acid derivatives | PNLIP, LIPC, GPR119 | IDO1 4434/4885DAO 1476/4885CYP17A1 285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.