SCHEMBL4631038

SCHEMBL4631038

C=Cc1ccc(C2(C)NC(=O)NC2=O)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.48
▸ KMT2A Q03164 1/20 0.48
▸ LMNA P02545 1/20 0.48
▸ TNKS O95271 1/20 0.44
▸ ALDH1A1 P00352 2/20 0.38
▸ MMP2 P08253 3/20 0.36
▸ MMP9 P14780 3/20 0.36
▸ ADAM17 P78536 1/20 0.36
▸ CACNA1F O60840 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ CYP2C9 P11712 1/20 0.34
▸ HTR2A P28223 1/20 0.34
▸ HRH1 P35367 1/20 0.34
▸ SCN1A P35498 1/20 0.34
▸ SCN4A P35499 1/20 0.34
▸ BLM P54132 1/20 0.34
▸ PMP22 Q01453 1/20 0.34
▸ CACNA1D Q01668 1/20 0.34
▸ KCNH2 Q12809 1/20 0.34
▸ CACNA1S Q13698 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20134878 0.78 LMNA (0.53) MEN1KMT2ALMNATNKSALDH1A1
SCHEMBL542561 0.78 LMNA (0.53) MEN1KMT2ALMNATNKSALDH1A1
Hydrochloric Acid SCHEMBL7029701 0.78 MEN1 (0.47) MEN1KMT2ALMNATNKSALDH1A1
SCHEMBL542817 0.77 LMNA (0.51) MEN1KMT2ALMNATNKSMMP2
SCHEMBL17054772 0.77 MEN1 (0.55) MEN1KMT2ALMNATNKSMMP2
SCHEMBL17570773 0.77 LMNA (0.51) MEN1KMT2ALMNATNKSMMP2
SCHEMBL7099930 0.77 LMNA (0.51) MEN1KMT2ALMNATNKSMMP2
SCHEMBL10131744 0.77 LMNA (0.51) MEN1KMT2ALMNATNKSALDH1A1
SCHEMBL542586 0.77 LMNA (0.51) MEN1KMT2ALMNATNKSMMP2
SCHEMBL17055125 0.77 MEN1 (0.55) MEN1KMT2ALMNATNKSMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1423008-B1 HIGHLY CROSSLINKED BIOCIDAL POLYSTYRENE HYDANTOIN PARTICLES UNIV AUBURN (US) 2008-02-13 — — EP claimed
EP-1423008-A2 HIGHLY CROSSLINKED BIOCIDAL POLYSTYRENE HYDANTOIN PARTICLES AUBURN UNIVERSITY (US) 2004-06-02 — — EP claimed
WO-2003053142-A2 HIGHLY CROSSLINKED BIOCIDAL POLYSTYRENE HYDANTOIN PARTICLES AUBURN UNIVERSITY (US) 2003-07-03 — — WO claimed
US-6548054-B2 Microbiocides, odor absorber AUBURN UNIVERSITY 2003-04-15 — — US claimed
US-20030044377-A1 Biocidal polystyrene hydantoin particles AUBURN UNIVERSITY 2003-03-06 — — US claimed
US-20030044378-A1 BIOCIDAL POLYSTYRENE HYDANTOIN PARTICLES AUBURN UNIVERSITY 2003-03-06 — — US claimed
US-6294185-B1 STABLE, INSOLUBLE BIOCIDES WHICH RELEASE ONLY SMALL AMOUNTS OF FREE HALOGEN,DISINFECTANTS AUBURN UNIVERSITY 2001-09-25 — — US claimed
US-5808089-A BIOCIDES AUBURN UNIVERSITY (US) 1998-09-15 — — US claimed
WO-1996008949-A2 NOVEL MONOMERIC AND POLYMERIC CYCLIC AMINE AND N-HALAMINE COMPOUNDS AUBURN UNIVERSITY (US) 1996-03-28 — — WO claimed
EP-4263441-A1 USE OF POLYMERIC BEADS TO REMOVE OXIDATIVE COMPOUNDS FROM LIQUIDS Auburn University (US) 2023-10-25 — — EP disclosed
WO-2022132872-A1 USE OF POLYMERIC BEADS TO REMOVE OXIDATIVE COMPOUNDS FROM LIQUIDS AUBURN UNIVERSITY (US) 2022-06-23 — — WO disclosed
US-20220193633-A1 USE OF POLYMERIC BEADS TO REMOVE OXIDATIVE COMPOUNDS FROM LIQUIDS AUBURN UNIVERSITY 2022-06-23 — — US disclosed
US-20170240435-A1 POLYMERIC HYBRID PARTICLE CONTAINING NANO PARTICLES AND USES HALOSOURCE, INC. (US) 2017-08-24 — — US disclosed
EP-3206496-A1 POLYMERIC HYBRID PARTICLE CONTAINING NANO PARTICLES AND USES Halosource, Inc. (US) 2017-08-23 — — EP disclosed
EP-0748223-A4 NOVEL POLYMERIC CYCLIC N-HALAMINE BIOCIDAL COMPOUNDS UNIV AUBURN (US) 1998-03-18 — — EP disclosed
US-5670646-A HEATING POLYVINYLACETOPHENONE UNDER VACUUM TO CRACK IT TO CORRESPONDING MONOMER, CONVERTING ACETO MOIETY TO HYDANTOIN OR TRIAZINE-2,4-DIONE AUBURN UNIVERSITY (US) 1997-09-23 — — US disclosed
EP-0748223-A1 NOVEL POLYMERIC CYCLIC N-HALAMINE BIOCIDAL COMPOUNDS AUBURN UNIVERSITY (US) 1996-12-18 — — EP disclosed
WO-1996008949-A2 NOVEL MONOMERIC AND POLYMERIC CYCLIC AMINE AND N-HALAMINE COMPOUNDS AUBURN UNIVERSITY (US) 1996-03-28 — — WO disclosed
US-5490983-A DISINFECTANTS AUBURN UNIVERSITY (US) 1996-02-13 — — US disclosed
WO-1994020118-A1 NOVEL POLYMERIC CYCLIC N-HALAMINE BIOCIDAL COMPOUNDS AUBURN UNIVERSITY (US) 1994-09-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030044377-A1 Biocidal polystyrene hydantoin particles PIR, HCN3, PNN MEN1 3907/4885KMT2A 1159/4885LMNA 3962/4885
US-20030044378-A1 BIOCIDAL POLYSTYRENE HYDANTOIN PARTICLES PIR, HCN3, PNN MEN1 3907/4885KMT2A 1159/4885LMNA 3962/4885
US-20170240435-A1 POLYMERIC HYBRID PARTICLE CONTAINING NANO PARTICLES AND USES DNMT1, DNMT3A, PUF60 MEN1 2050/4885KMT2A 170/4885LMNA 3373/4885
US-20220193633-A1 USE OF POLYMERIC BEADS TO REMOVE OXIDATIVE COMPOUNDS FROM LIQUIDS LPO, GPX4, CAT MEN1 4819/4885KMT2A 1290/4885LMNA 4546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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