SCHEMBL4631077

SCHEMBL4631077

C=C(C)C(=O)NCCC[Si](C)(OC(C)=O)OC(C)=O

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
MAPK1 P28482 1/20 0.36
HIF1A Q16665 1/20 0.36
PAOX Q6QHF9 3/20 0.32
ADRA1A P35348 1/20 0.31
ACHE P22303 1/20 0.31
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19548059 0.86 KDM4E (0.36) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL167885 0.84 KDM4E (0.38) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL170046 0.84 ALDH1A1 (0.39) KDM4EMAPK1HIF1AACHE
SCHEMBL441807 0.83 KDM4E (0.32) KDM4EMAPK1HIF1AACHE
SCHEMBL11128147 0.81 ACHE (0.33) KDM4EMAPK1HIF1APAOXACHE
SCHEMBL28665274 0.80 KDM4E (0.38) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL25389669 0.79 ALDH1A1 (0.38) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL4631131 0.79 KDM4E (0.41) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL12094903 0.79 KDM4E (0.34) KDM4EMAPK1HIF1AACHE
SCHEMBL21373911 0.78 KDM4E (0.37) KDM4EMAPK1HIF1APAOXADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7439311-B2 Superior in viscosity stability, water resistance of its film and ability of preventing a scale from depositing on the inner wall of a polymerization reactor; polyvinyl alcohol obtained through saponification of a polyvinyl ester that contains monomer units having a silyl group KURARAY CO., LTD. (JP) 2008-10-21 US disclosed
US-20080119623-A1 Superior in viscosity stability, water resistance of its film and ability of preventing a scale from depositing on the inner wall of a polymerization reactor; polyvinyl alcohol obtained through saponification of a polyvinyl ester that contains monomer units having a silyl group KURARAY CO., LTD. (JP) 2008-05-22 US disclosed
EP-1553107-B1 Anti-fouling agent and method for producing the same KURARAY CO (JP) 2008-05-21 EP disclosed
US-6962955-B2 Vinyl alcohol polymer and process for producing vinyl alcohol polymer KURARAY CO., LTD. (JP) 2005-11-08 US disclosed
EP-1380599-B1 Polyvinyl alcohol and method for producing polyvinyl alcohol KURARAY CO (JP) 2005-09-21 EP disclosed
EP-1380600-B1 Polyvinyl alcohol and method for producing polyvinyl alcohol KURARAY CO (JP) 2005-09-21 EP disclosed
US-20050175795-A1 Vinyl alcohol polymer and process for producing vinyl alcohol polymer KURARAY CO., LTD. (JP) 2005-08-11 US disclosed
EP-1553107-A1 Anti-fouling agent and method for producing the same KURARAY CO., LTD. (JP) 2005-07-13 EP disclosed
US-20050148736-A1 superior in viscosity stability, water resistance of its film and ability of preventing a scale from depositing on the inner wall of a polymerization reactor; polyvinyl alcohol obtained through saponification of a polyvinyl ester that contains monomer units having a silyl group KURARAY CO., LTD. (JP) 2005-07-07 US disclosed
US-20040054069-A1 Polyvinyl alcohol and method for producing polyvinyl alcohol KURARY CO., LTD. (JP) 2004-03-18 US disclosed
US-20040009357-A1 Vinyl alcohol polymer and process for producing vinyl alcohol polymer KURARY CO., LTD. (JP) 2004-01-15 US disclosed
EP-1380599-A1 Polyvinyl alcohol and method for producing polyvinyl alcohol KURARAY CO., LTD. (JP) 2004-01-14 EP disclosed
EP-1380600-A1 Polyvinyl alcohol and method for producing polyvinyl alcohol KURARAY CO., LTD. (JP) 2004-01-14 EP disclosed