Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25389669 | 0.95 | ALDH1A1 (0.38) | ALDH1A1KDM4EMAPK1HIF1AACHE | |
| SCHEMBL25389099 | 0.93 | KDM4E (0.39) | ALDH1A1KDM4EMAPK1HIF1AEPHX1 | |
| SCHEMBL25388356 | 0.93 | KDM4E (0.39) | ALDH1A1KDM4EMAPK1HIF1AEPHX1 | |
| SCHEMBL23031229 | 0.91 | TSHR (0.42) | ALDH1A1KDM4ETSHR | |
| SCHEMBL169376 | 0.86 | ALDH1A1 (0.34) | ALDH1A1KDM4EMAPK1HIF1AACHE | |
| SCHEMBL441807 | 0.84 | KDM4E (0.32) | KDM4EMAPK1HIF1AACHE | |
| SCHEMBL4631077 | 0.84 | KDM4E (0.36) | KDM4EMAPK1HIF1AACHE | |
| SCHEMBL23031294 | 0.84 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL135382 | 0.84 | ALDH1A1 (0.35) | ALDH1A1KDM4EMAPK1HIF1AACHE | |
| SCHEMBL11128147 | 0.83 | ACHE (0.33) | KDM4EMAPK1HIF1AACHEEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2158283-B1 | MOISTURE-CURABLE, GRAFT-MODIFIED RESIN COMPOSITION, PROCESS FOR ITS MANUFACTURE AND PROCESS FOR BONDING SUBSTRATES EMPLOYING THE RESIN COMPOSITION | MOMENTIVE PERFORMANCE MAT INC (US) | 2017-10-18 | — | — | EP | claimed |
| US-8063140-B2 | Moisture-curable, graft-modified resin composition, process for its manufacture and process for bonding substrates employing the resin composition | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-11-22 | — | — | US | claimed |
| EP-2158283-A1 | MOISTURE-CURABLE, GRAFT-MODIFIED RESIN COMPOSITION, PROCESS FOR ITS MANUFACTURE AND PROCESS FOR BONDING SUBSTRATES EMPLOYING THE RESIN COMPOSITION | Momentive Performance Materials Inc. (US) | 2010-03-03 | — | — | EP | claimed |
| EP-2084217-A2 | PROCESS FOR CROSSLINKING THERMOPLASTIC POLYMERS WITH SILANES EMPLOYING PEROXIDE BLENDS, THE RESULTING CROSSLINKED THERMOPLASTIC POLYMER COMPOSITION AND ARTICLES MADE THEREFROM | Momentive Performance Materials Inc. (US) | 2009-08-05 | — | — | EP | claimed |
| WO-2008156611-A1 | MOISTURE-CURABLE, GRAFT-MODIFIED RESIN COMPOSITION, PROCESS FOR ITS MANUFACTURE AND PROCESS FOR BONDING SUBSTRATES EMPLOYING THE RESIN COMPOSITION | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-12-24 | — | — | WO | claimed |
| US-20080311419-A1 | Moisture-curable, graft-modified resin composition, process for its manufacture and process for bonding substrates employing the resin composition | MOMENTIVE PERFORMANCE MATERIALS INC. | 2008-12-18 | — | — | US | claimed |
| WO-2008060508-A2 | PROCESS FOR CROSSLINKING THERMOPLASTIC POLYMERS WITH SILANES EMPLOYING PEROXIDE BLENDS, THE RESULTING CROSSLINKED THERMOPLASTIC POLYMER COMPOSITION AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-05-22 | — | — | WO | claimed |
| US-20080114134-A1 | Process for crosslinking thermoplastic polymers with silanes employing peroxide blends, the resulting crosslinked thermoplastic polymer composition and articles made therefrom | GENERAL ELECTRIC COMPANY (US) | 2008-05-15 | — | — | US | claimed |
| EP-3782599-B1 | DENTAL POLYMERIZABLE COMPOSITION BASED ON CONDENSED SILANES | VOCO GMBH (DE) | 2025-09-17 | — | — | EP | disclosed |
| CN-119301322-A | Glass cloth treating liquid and surface treated glass cloth | 信越化学工业株式会社 | 2025-01-10 | — | — | CN | disclosed |
| CN-118804956-A | Composition comprising an organosilicon compound containing methacrylamide groups and article surface-treated with said composition | 信越化学工业株式会社 | 2024-10-18 | — | — | CN | disclosed |
| US-11992538-B2 | Polymerizable dental composition based on condensed silanes | VOCO GMBH (DE) | 2024-05-28 | — | — | US | disclosed |
| WO-2024094292-A1 | MULTI-STAGE COPOLYMERS AS BINDER FOR COATING AGENTS | WACKER CHEMIE AG (DE) | 2024-05-10 | — | — | WO | disclosed |
| WO-2023219000-A1 | GLASS CLOTH TREATMENT LIQUID AND SURFACE TREATED GLASS CLOTH | 信越化学工業株式会社 | 2023-11-16 | — | — | WO | disclosed |
| EP-0123927-B1 | WATER RESISTANT COMPOSITIONS | KURARAY CO., LTD. (JP) | 1990-07-25 | — | — | EP | disclosed |
| US-4708947-A | POLYVINYL ALCOHOL, A CHITOSAN AND AN ALDEHYDE | KURARAY CO., LTD. (JP) | 1987-11-24 | — | — | US | disclosed |
| EP-0187673-A2 | Water resistant composition and heat-sensitive recording sheet containing the same | KURARAY CO., LTD. (JP) | 1986-07-16 | — | — | EP | disclosed |
| US-4567221-A | DEFOGGING AGENTS, SOLIDIFICATION OF SOILS | KURARAY CO., LTD. (JP) | 1986-01-28 | — | — | US | disclosed |
| EP-0123927-A2 | Water resistant compositions | KURARAY CO., LTD. (JP) | 1984-11-07 | — | — | EP | disclosed |
| US-4389432-A | POLYSILOXANES CURED RESIN | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1983-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11992538-B2 | Polymerizable dental composition based on condensed silanes | NCAPH, RCC1, NCAPD2 | ALDH1A1 1481/4885KDM4E 3768/4885MAPK1 4001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.