Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5639725 | 0.80 | CYP1A2 (0.59) | ALDH1A1HSD17B10L3MBTL1S1PR1CYP1A2 | |
| SCHEMBL4630816 | 0.77 | ALDH1A1 (0.54) | ALDH1A1HSD17B10L3MBTL1S1PR1CYP1A2 | |
| SCHEMBL4631244 | 0.76 | BCAT2 (0.56) | ALDH1A1HSD17B10MAPTKDM4ENPC1 | |
| SCHEMBL4360317 | 0.76 | ALDH1A1 (0.48) | ALDH1A1HSD17B10L3MBTL1S1PR1CYP1A2 | |
| SCHEMBL4631250 | 0.76 | ALDH1A1 (0.48) | ALDH1A1HSD17B10L3MBTL1CYP1A2CYP1A1 | |
| SCHEMBL4954449 | 0.74 | HRH3 (0.47) | CYP1A2CYP1A1CYP1B1PTGES2MAPT | |
| SCHEMBL6480845 | 0.74 | ALDH1A1 (0.83) | ALDH1A1HSD17B10L3MBTL1KDM4ENPC1 | |
| SCHEMBL20717544 | 0.73 | APP (0.59) | ALDH1A1BACE1PTGES2MAPTNPC1 | |
| SCHEMBL562815 | 0.72 | APP (0.55) | ALDH1A1HSD17B10CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL31264295 | 0.72 | ALDH1A1 (0.79) | ALDH1A1HSD17B10L3MBTL1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575922-B1 | BIPHENYL DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-05-14 | — | — | EP | claimed |
| US-7241721-B2 | carboxamide derivatives as active ingredients which have microbiocidal activity, in particular fungicidal activity | SYNGENTA CROP PROTECTION, INC. (US) | 2007-07-10 | — | — | US | claimed |
| US-20080076664-A1 | Fungicidal Compositions | SYNGENTA CROP PROTECTION, INC. | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076664-A1 | Fungicidal Compositions | AKR7A2, CYP51A1, TUBA3C | ALDH1A1 1173/4885HSD17B10 394/4885BACE1 424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.