SCHEMBL5639725

SCHEMBL5639725

CC#Cc1ccc(-c2ccccc2N)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.59
CYP1A1 P04798 2/20 0.59
CYP1B1 Q16678 2/20 0.59
ALDH1A1 P00352 4/20 0.54
HSD17B10 Q99714 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.44
MAPT P10636 2/20 0.42
SMN1; SMN2 Q16637 3/20 0.38
KDM4E B2RXH2 2/20 0.38
NPC1 O15118 2/20 0.38
HPGD P15428 2/20 0.38
CYP3A4 P08684 2/20 0.38
MEN1 O00255 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
KMT2A Q03164 1/20 0.38
APP P05067 2/20 0.38
BCHE P06276 1/20 0.37
ACHE P22303 1/20 0.37
DHFR P00374 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4630816 0.81 ALDH1A1 (0.54) CYP1A2CYP1A1CYP1B1ALDH1A1HSD17B10
SCHEMBL4631250 0.80 ALDH1A1 (0.48) CYP1A2CYP1A1CYP1B1ALDH1A1HSD17B10
SCHEMBL4360317 0.80 ALDH1A1 (0.48) CYP1A2CYP1A1CYP1B1ALDH1A1HSD17B10
SCHEMBL4631247 0.80 ALDH1A1 (0.48) CYP1A2CYP1A1CYP1B1ALDH1A1HSD17B10
SCHEMBL6480845 0.78 ALDH1A1 (0.83) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2KDM4E
SCHEMBL19604555 0.77 CYP1A1 (0.59) CYP1A2CYP1A1CYP1B1ALDH1A1L3MBTL1
SCHEMBL29510158 0.77 ALDH1A1 (0.71) ALDH1A1HSD17B10L3MBTL1MAPTSMN1; SMN2
SCHEMBL599657 0.77 ALDH1A1 (0.71) ALDH1A1HSD17B10L3MBTL1MAPTSMN1; SMN2
SCHEMBL31264295 0.76 ALDH1A1 (0.79) ALDH1A1HSD17B10L3MBTL1MAPTSMN1; SMN2
SCHEMBL29429038 0.76 ALDH1A1 (0.58) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7241721-B2 carboxamide derivatives as active ingredients which have microbiocidal activity, in particular fungicidal activity SYNGENTA CROP PROTECTION, INC. (US) 2007-07-10 US claimed