Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 13/20 | 0.50 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.48 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.48 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.48 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.48 |
| ▸ | SRD5A1 | P18405 | 5/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 9/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629038 | 0.84 | CYP11B2 (0.36) | CYP11B2BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL2051397 | 0.81 | BMPR1B (0.50) | CYP11B2BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL25921027 | 0.81 | CYP11B2 (0.49) | CYP11B2BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL30404193 | 0.81 | BMPR1B (0.50) | CYP11B2BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL31178367 | 0.81 | CYP11B2 (0.49) | CYP11B2BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL25317019 | 0.81 | CYP11B2 (0.49) | CYP11B2BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL21831983 | 0.81 | CYP11B2 (0.49) | CYP11B2BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL9836345 | 0.79 | CYP11B2 (0.47) | CYP11B2BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL26023601 | 0.79 | CYP11B2 (0.34) | CYP11B2BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL26023616 | 0.75 | CYP11B2 (0.32) | CYP11B2BMPR1BBMPR1AACVRL1ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151436-A2 | NOVEL COMPOUNDS, METHOD FOR USE THEM AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | EUROSCREEN S.A. (BE) | 2011-12-08 | — | — | WO | disclosed |