Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46307 | 0.83 | GPR119 (0.41) | SMN1; SMN2NPC1TP53PKMSTAT3 | |
| SCHEMBL411138 | 0.82 | GRIN2D (0.38) | NPC1RAB9AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL469887 | 0.82 | ROCK2 (0.33) | GRM5ROCK2 | |
| SCHEMBL6893476 | 0.74 | GPR119 (0.41) | SMN1; SMN2NPC1TP53PKMSTAT3 | |
| SCHEMBL38109 | 0.73 | — | — | |
| SCHEMBL46339 | 0.72 | GRIN2D (0.46) | SMN1; SMN2NPC1TP53PKMSTAT3 | |
| SCHEMBL14734000 | 0.72 | GPR119 (0.55) | SMN1; SMN2GPR119GRIN2DGRIN3BGRIN1 | |
| SCHEMBL16260556 | 0.70 | GPR119 (0.49) | GPR119GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16260503 | 0.70 | GPR119 (0.49) | GPR119GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL19454936 | 0.70 | TDO2 (0.48) | SMN1; SMN2NPC1TP53PKMSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151436-A2 | NOVEL COMPOUNDS, METHOD FOR USE THEM AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | EUROSCREEN S.A. (BE) | 2011-12-08 | — | — | WO | disclosed |