SCHEMBL4631963

SCHEMBL4631963

OC/C=C(/Br)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 2/20 0.38
PTPN1 P18031 1/20 0.38
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
NCOR2 Q9Y618 1/20 0.36
MAPK1 P28482 4/20 0.36
CES1 P23141 4/20 0.36
MAPT P10636 2/20 0.36
KMT2A Q03164 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
CYP3A4 P08684 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
ALDH1A1 P00352 4/20 0.35
NPC1 O15118 1/20 0.35
S1PR2 O95136 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4631968 1.00 GSK3B (0.38) GSK3BPTPN1HDAC3HDAC1HDAC2
SCHEMBL8997899 0.79 ALDH1A1 (0.41) GSK3BPTPN1MAPK1CES1MAPT
SCHEMBL8997895 0.79 ALDH1A1 (0.41) GSK3BPTPN1MAPK1CES1MAPT
SCHEMBL6268910 0.77 DRD2 (0.38) GSK3BPTPN1MAPK1CES1MAPT
SCHEMBL8815111 0.75 NFE2L2 (0.44) GSK3BPTPN1HDAC3HDAC1HDAC2
SCHEMBL1792813 0.75 AKT1 (0.41) GSK3BPTPN1HDAC3HDAC1HDAC2
SCHEMBL1792814 0.75 AKT1 (0.41) GSK3BPTPN1HDAC3HDAC1HDAC2
SCHEMBL4630812 0.75 MTNR1A (0.48) HDAC3HDAC1HDAC2NCOR2TDP1
SCHEMBL10674358 0.74 CYP3A4 (0.42) SMN1; SMN2TDP1KDM4ECYP3A4HPGD
SCHEMBL10674369 0.74 CYP3A4 (0.42) SMN1; SMN2TDP1KDM4ECYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1927889-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2014-06-25 EP disclosed
EP-1927889-A1 Lithographic printing plate precursor FUJIFILM Corporation (JP) 2008-06-04 EP disclosed
EP-1091253-B1 Plate making process for planographic plate, automatic developing apparatus and recording medium FUJI PHOTO FILM CO LTD (JP) 2005-03-30 EP disclosed
US-6558873-B1 Interlayer containing a compound capable of forming a complex with aluminum and a photopolymerizable photosensitive layer containing a photopolymerization initiator, an addition polymerizable compound capable of complexing with aluminum FUJI PHOTO FILM CO., LTD. (JP) 2003-05-06 US disclosed
EP-1091253-A2 Plate making process for planographic plate, automatic developing apparatus and recording medium FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
EP-1091251-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
US-6191184-B1 SUITABLE FOR FORMATION OF LIQUID CRYSTAL DISPLAY (LCD) SPACERS OR PROTECTIVE LAYERS; PHOTOSETTING PROPERTIES ADHESIVENESS TO SUBSTRATES; MECHANICAL CHARACTERISTICS, STORAGE STABILITY SHOW EXCELLENT WORKING FUJI PHOTO FILM CO., LTD. (JP) 2001-02-20 US disclosed
US-4687727-A Light-sensitive planographic printing plate with layer of diazo resin containing photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1987-08-18 US disclosed
US-4511645-A ALLYL METHACRYLATE-METHACRYLIC ACID COPOLYMER, CURING AGENT, PHOTOINITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1985-04-16 US disclosed