Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6254912 | 0.84 | — | — | |
| SCHEMBL12561788 | 0.83 | THRB (0.38) | THRBMAPK1HIF1A | |
| SCHEMBL12561792 | 0.79 | THRB (0.40) | THRBMAPK1HIF1A | |
| SCHEMBL16301006 | 0.75 | THRB (0.38) | THRBMAPK1HIF1A | |
| SCHEMBL1502718 | 0.75 | THRB (0.38) | THRBMAPK1HIF1A | |
| SCHEMBL27165259 | 0.74 | ALDH1A1 (0.37) | THRBMAPK1HIF1A | |
| SCHEMBL13714627 | 0.73 | THRB (0.37) | THRBMAPK1HIF1A | |
| SCHEMBL4353475 | 0.73 | THRB (0.32) | THRB | |
| SCHEMBL7085097 | 0.72 | MAPK1 (0.38) | THRBMAPK1HIF1A | |
| SCHEMBL1597489 | 0.72 | MAPK1 (0.39) | MAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569966-B1 | RING-OPENED AZLACTONE INITIATORS FOR ATOM TRANSFER RADICAL POLYMERIZATION | 3M INNOVATIVE PROPERTIES CO (US) | 2008-05-28 | — | — | EP | disclosed |
| US-20080027210-A1 | RING-OPENED AZLACTONE INITIATORS FOR ATOM TRANSFER RADICAL POLYMERIZATION | 3M INNOVATIVE PROPERTIES COMPANY | 2008-01-31 | — | — | US | disclosed |
| US-7294742-B2 | Ring-opened azlactone initiators for atom transfer radical polymerization | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-11-13 | — | — | US | disclosed |
| EP-1569967-B1 | AZLACTONE INITIATORS FOR ATOM TRANSFER RADICAL POLYMERIZATION | 3M INNOVATIVE PROPERTIES CO (US) | 2006-07-19 | — | — | EP | disclosed |
| US-6969749-B2 | Azlactone initiators for atom transfer radical polymerization | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-11-29 | — | — | US | disclosed |
| US-20050159569-A1 | Ring-opened azlactone initiators for atom transfer radical polymerization | 3M INNOVATIVE PROPERTIES COMPANY | 2005-07-21 | — | — | US | disclosed |
| US-20050065300-A1 | Azlactone initiators for atom transfer radical polymerization | 3M INNOVATIVE PROPERTIES COMPANY | 2005-03-24 | — | — | US | disclosed |
| US-20040116633-A1 | Ring-opened azlactone initiators for atom transfer radical polymerization | 3M INNOVATIVE PROPERTIES COMPANY | 2004-06-17 | — | — | US | disclosed |
| US-20040116616-A1 | Azlactone initiators for atom transfer radical polymerization | 3M INNOVATIVE PROPERTIES COMPANY | 2004-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159569-A1 | Ring-opened azlactone initiators for atom transfer radical polymerization | TTL, TERT, AZI2 | THRB 2474/4885MAPK1 3105/4885HIF1A 2921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.