Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 2/20 | 0.31 |
| ▸ | LDHB | P07195 | 2/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2655839 | 0.80 | MAOA (0.53) | DDB1CRBNMAOAMAOBCYP1A2 | |
| SCHEMBL4842682 | 0.77 | ALDH1A1 (0.38) | — | |
| SCHEMBL2538752 | 0.77 | DDB1 (0.53) | DDB1CRBNMAOAMAOBCYP1A2 | |
| SCHEMBL14595419 | 0.69 | MAOA (0.38) | MAOAMAOB | |
| SCHEMBL2579025 | 0.69 | MAOA (0.38) | MAOAMAOB | |
| SCHEMBL17784105 | 0.66 | BACE1 (0.32) | — | |
| SCHEMBL2581431 | 0.66 | MAOB (0.40) | MAOAMAOBMAPTTRPA1 | |
| SCHEMBL2586878 | 0.63 | MAOA (0.33) | DDB1CRBNMAOAMAOBCYP3A4 | |
| Acetonitrile SCHEMBL27498741 | 0.63 | TRPA1 (0.59) | MAOAMAOBTRPA1 | |
| SCHEMBL514630 | 0.62 | CYP1A2 (0.53) | DDB1CRBNCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924561-A2 | 6-ARYLALKYLAMINO- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | Eli Lilly & Company (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007028083-A2 | 6-ARYLALKYLAMINO- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2007-03-08 | — | — | WO | disclosed |