Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 5/20 | 0.43 |
| ▸ | MME | P08473 | 5/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | GNPAT | O15228 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4424322 | 0.96 | MAPT (0.60) | MAPTPTGS2BLMKDM4ETHRB | |
| SCHEMBL18263621 | 0.96 | MAPT (0.60) | MAPTPTGS2BLMKDM4ETHRB | |
| SCHEMBL29774451 | 0.91 | PTGS1 (0.52) | MAPTPTGS2BLMKDM4ETHRB | |
| SCHEMBL17287153 | 0.90 | PTGS1 (0.57) | MAPTPTGS2BLMKDM4ETHRB | |
| SCHEMBL30065558 | 0.90 | PTGS1 (0.54) | MAPTPTGS2BLMKDM4ETHRB | |
| SCHEMBL14647811 | 0.84 | MAPT (0.54) | MAPTPTGS2BLMKDM4ETHRB | |
| SCHEMBL236405 | 0.82 | PTGS1 (0.67) | MAPTPTGS2BLMKDM4ETHRB | |
| SCHEMBL20787749 | 0.82 | PTGS1 (0.67) | MAPTPTGS2BLMKDM4ETHRB | |
| SCHEMBL29436285 | 0.82 | SIRT5 (0.46) | MAPTPTGS2BLMKDM4ETHRB | |
| SCHEMBL31134521 | 0.82 | SIRT5 (0.46) | MAPTPTGS2BLMKDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1584615-B1 | Use of dimercaptoamides for permanently deforming of keratinic fibres | OREAL (FR) | 2008-05-28 | — | — | EP | claimed |
| EP-1584615-A1 | Use of dimercaptoamides for permanently deforming of keratinic fibres | L'OREAL (FR) | 2005-10-12 | — | — | EP | claimed |
| EP-1584615-B1 | Use of dimercaptoamides for permanently deforming of keratinic fibres | OREAL (FR) | 2008-05-28 | — | — | EP | disclosed |
| EP-1584615-A1 | Use of dimercaptoamides for permanently deforming of keratinic fibres | L'OREAL (FR) | 2005-10-12 | — | — | EP | disclosed |