Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | GNPAT | O15228 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | IL23R | Q5VWK5 | 5/20 | 0.39 |
| ▸ | NPY4R | P50391 | 8/20 | 0.38 |
| ▸ | NPY1R | P25929 | 5/20 | 0.38 |
| ▸ | NPY2R | P49146 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29436284 | 1.00 | SIRT5 (0.46) | SIRT5PTGS1GSTK1SIRT6SIRT1 | |
| SCHEMBL29552728 | 1.00 | SIRT5 (0.46) | SIRT5PTGS1GSTK1SIRT6SIRT1 | |
| SCHEMBL31134521 | 1.00 | SIRT5 (0.46) | SIRT5PTGS1GSTK1SIRT6SIRT1 | |
| SCHEMBL29696186 | 0.94 | SIRT5 (0.50) | SIRT5SIRT6SIRT1GNPATNPY4R | |
| SCHEMBL31391112 | 0.90 | PTGS1 (0.46) | SIRT5PTGS1GSTK1NPY4RNPY1R | |
| SCHEMBL31391130 | 0.88 | PTGS1 (0.50) | SIRT5PTGS1GSTK1NPY4RNPY1R | |
| SCHEMBL29947102 | 0.88 | SMN1; SMN2 (0.54) | SIRT5SIRT6SIRT1GNPATKDM4E | |
| SCHEMBL6756643 | 0.88 | SMN1; SMN2 (0.50) | SIRT5SIRT6SIRT1GNPATKDM4E | |
| SCHEMBL29947125 | 0.88 | SMN1; SMN2 (0.54) | SIRT5SIRT6SIRT1GNPATKDM4E | |
| SCHEMBL29947066 | 0.88 | SMN1; SMN2 (0.54) | SIRT5SIRT6SIRT1GNPATKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260014263-A1 | PEPTIDE OLIGONUCLEOTIDE CONJUGATES | SAREPTA THERAPEUTICS, INC. (US) | 2026-01-15 | — | — | US | disclosed |
| US-12239715-B2 | Peptide oligonucleotide conjugates | SAREPTA THERAPEUTICS, INC. (US) | 2025-03-04 | — | — | US | disclosed |
| EP-4306538-A2 | PEPTIDE OLIGONUCLEOTIDE CONJUGATES | Sarepta Therapeutics, Inc. (US) | 2024-01-17 | — | — | EP | disclosed |
| EP-3297649-B1 | PEPTIDE OLIGONUCLEOTIDE CONJUGATES | SAREPTA THERAPEUTICS INC (US) | 2023-10-11 | — | — | EP | disclosed |
| US-20230310625-A1 | Peptide Oligonucleotide Conjugates | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2023-10-05 | — | — | US | disclosed |
| US-11672871-B2 | Peptide oligonucleotide conjugates | SAREPTA THERAPEUTICS, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| CN-114681621-A | Peptide oligonucleotide conjugates | 萨勒普塔医疗公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-107921092-B | Peptide oligonucleotide conjugates | 萨勒普塔医疗公司 | 2022-04-08 | — | — | CN | disclosed |
| US-20220072143-A1 | Peptide Oligonucleotide Conjugates | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2022-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220072143-A1 | Peptide Oligonucleotide Conjugates | MYOF, MUSK, MTPN | SIRT5 3752/4885PTGS1 4612/4885GSTK1 1812/4885 |
| US-20230310625-A1 | Peptide Oligonucleotide Conjugates | MYOF, MUSK, MTPN | SIRT5 3752/4885PTGS1 4612/4885GSTK1 1812/4885 |
| US-12239715-B2 | Peptide oligonucleotide conjugates | MYOF, MUSK, MTPN | SIRT5 3752/4885PTGS1 4612/4885GSTK1 1812/4885 |
| US-11672871-B2 | Peptide oligonucleotide conjugates | MYOF, MUSK, MTPN | SIRT5 3752/4885PTGS1 4612/4885GSTK1 1812/4885 |
| US-20260014263-A1 | PEPTIDE OLIGONUCLEOTIDE CONJUGATES | SSU72, TNNC1, MUSK | SIRT5 4355/4885PTGS1 4452/4885GSTK1 2901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.