Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | LTA4H | P09960 | 2/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.56 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.55 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylamine SCHEMBL9872082 | 0.95 | KDM4E (0.66) | LSSKDM4EALDH1A1SMN1; SMN2LTA4H | |
| Methylamine SCHEMBL27703437 | 0.92 | LSS (0.73) | LSSKDM4EALDH1A1SMN1; SMN2LTA4H | |
| SCHEMBL4632841 | 0.92 | LSS (0.79) | LSSKDM4EALDH1A1SMN1; SMN2LTA4H | |
| Ethylamine SCHEMBL9871196 | 0.91 | LTA4H (0.73) | LSSKDM4EALDH1A1SMN1; SMN2LTA4H | |
| SCHEMBL9851879 | 0.86 | LSS (0.70) | LSSKDM4EALDH1A1SMN1; SMN2LTA4H | |
| SCHEMBL13886633 | 0.85 | LTA4H (0.83) | LSSKDM4EALDH1A1SMN1; SMN2LTA4H | |
| SCHEMBL9851880 | 0.85 | LSS (0.68) | LSSKDM4EALDH1A1SMN1; SMN2LTA4H | |
| SCHEMBL9491062 | 0.85 | LSS (0.68) | LSSKDM4EALDH1A1SMN1; SMN2LTA4H | |
| SCHEMBL9851898 | 0.85 | LSS (0.68) | LSSKDM4EALDH1A1SMN1; SMN2LTA4H | |
| SCHEMBL9851895 | 0.85 | LSS (0.68) | LSSKDM4EALDH1A1SMN1; SMN2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021429-A | Histamine h2-antagonists; antisecretory-antiallergen agent; skin disorders and peptic ulcers | ALLEN & HANSBURYS LIMITED (GB) | 1991-06-04 | — | — | US | disclosed |