Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4288847 | 0.84 | MMP13 (0.58) | SMN1; SMN2ALDH1A1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL4632986 | 0.82 | ALDH1A1 (0.60) | L3MBTL1SMN1; SMN2POLBALDH1A1KMT2A | |
| SCHEMBL12472899 | 0.76 | ALDH1A1 (0.59) | LMNAL3MBTL1SMN1; SMN2POLBTHRB | |
| SCHEMBL168618 | 0.76 | MEN1 (0.63) | LMNASMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL8358839 | 0.75 | MMP13 (0.71) | LMNAL3MBTL1SMN1; SMN2POLBTHRB | |
| SCHEMBL5223245 | 0.75 | L3MBTL1 (0.52) | LMNAL3MBTL1SMN1; SMN2POLBTHRB | |
| SCHEMBL3144624 | 0.74 | CNR1 (0.41) | LMNAL3MBTL1SMN1; SMN2POLBTHRB | |
| SCHEMBL20029114 | 0.74 | ACR (0.43) | L3MBTL1SMN1; SMN2POLBALDH1A1KMT2A | |
| SCHEMBL27363106 | 0.74 | HDAC6 (0.35) | LMNASMN1; SMN2POLBKMT2A | |
| SCHEMBL6077802 | 0.73 | L3MBTL1 (0.77) | LMNAL3MBTL1SMN1; SMN2POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928859-A1 | PYRAZOLE DERIVATES AS CANNABINOID RECEPTOR MODULATORS | Carex SA (FR) | 2008-06-11 | — | — | EP | disclosed |
| WO-2006133926-A1 | PYRAZOLE DERIVATES AS CANNABINOID RECEPTOR MODULATORS | CAREX SA (FR) | 2006-12-21 | — | — | WO | disclosed |