Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.37 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4632904 | 0.91 | LMNA (0.40) | LMNAALDH1A1KMT2AHTTGSTP1 | |
| SCHEMBL4632328 | 0.80 | KMT2A (0.49) | LMNAALDH1A1KMT2AGSTP1GSTM2 | |
| SCHEMBL3555267 | 0.80 | ALDH1A1 (0.34) | LMNAALDH1A1KMT2AHTTNPC1 | |
| SCHEMBL4777017 | 0.79 | NPC1 (0.34) | LMNAALDH1A1KMT2AHTTNPC1 | |
| SCHEMBL4592596 | 0.79 | MAP4K1 (0.36) | LMNAALDH1A1KMT2AHTTNPC1 | |
| SCHEMBL4664889 | 0.75 | LMNA (0.40) | LMNAALDH1A1KMT2AHTTNPC1 | |
| SCHEMBL5901211 | 0.74 | ALDH1A1 (0.47) | LMNAALDH1A1KMT2AHTTNPSR1 | |
| SCHEMBL4633149 | 0.74 | LMNA (0.43) | LMNAALDH1A1KMT2AHTTGSTP1 | |
| SCHEMBL4633318 | 0.70 | MAP4K1 (0.34) | ALDH1A1 | |
| SCHEMBL4632242 | 0.70 | KMT2A (0.53) | LMNAALDH1A1KMT2AHTTGSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1926714-A1 | ISOTOPICALLY SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | Nycomed GmbH (DE) | 2008-06-04 | — | — | EP | disclosed |
| WO-2007023135-A1 | ISOTOPICALLY SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | NYCOMED GMBH (DE) | 2007-03-01 | — | — | WO | disclosed |