Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.40 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | CLK3 | P49761 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL9539322 | 0.92 | ALDH1A1 (0.33) | PTPN1GP6KIF11NOTUMNPC1 | |
| SCHEMBL198144 | 0.87 | KCNN4 (0.32) | — | |
| SCHEMBL16975529 | 0.83 | KIF11 (0.37) | PTPN5KIF11CYP3A4NPC1GAA | |
| SCHEMBL5633434 | 0.81 | TAAR1 (0.39) | KIF11 | |
| SCHEMBL1132121 | 0.80 | — | — | |
| Phenylboronic Acid SCHEMBL988759 | 0.75 | CA4 (0.44) | — | |
| SCHEMBL30139540 | 0.74 | KIF11 (0.40) | KIF11KDM4ENPC1 | |
| SCHEMBL29518677 | 0.72 | — | — | |
| SCHEMBL8987735 | 0.71 | ESR1 (0.41) | CYP3A4KDM4EMAPTKMT2A | |
| SCHEMBL4655029 | 0.69 | GP6 (0.49) | PTPN1GP6CYP3A4FGFR1DYRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931648-A2 | PROCESSES FOR THE SYNTHESIS OF 5-PHENYL -1 TRITYL-1H-TETRAZOLE | Teva Pharmaceutical Industries Ltd. (IL) | 2008-06-18 | — | — | EP | claimed |
| WO-2008027385-A2 | PROCESSES FOR THE SYNTHESIS OF 5-PHENYL -1 TRITYL-1H-TETRAZOLE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-03-06 | — | — | WO | claimed |
| EP-1509517-A2 | NOVEL SYNTHESIS OF IRBESARTAN | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2005-03-02 | — | — | EP | claimed |
| WO-2004065383-A2 | NOVEL SYNTHESIS OF IRBESARTAN | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2004-08-05 | — | — | WO | claimed |
| EP-0654027-A1 | PRODRUGS OF IMIDAZOLE CARBOXYLIC ACIDS AS ANGIOTENSIN II RECEPTOR ANTAGONISTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-05-24 | — | — | EP | disclosed |