SCHEMBL4633890

SCHEMBL4633890

COc1ccccc1OP(=O)(OCl)OCl

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA12 O43570 1/20 0.52
CA4 P22748 1/20 0.52
CA14 Q9ULX7 1/20 0.52
CYP1A2 P05177 2/20 0.50
CYP3A4 P08684 2/20 0.50
CYP2C19 P33261 2/20 0.50
HPGD P15428 2/20 0.46
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
MAPK1 P28482 3/20 0.45
LMNA P02545 1/20 0.43
HTT P42858 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP2C9 P11712 1/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19809 0.87 CA1 (0.62) CA1CA2CA7CA9CA12
SCHEMBL3762104 0.80 KDM4E (0.45) CYP1A2CYP3A4CYP2C19HPGDKMT2A
SCHEMBL4633888 0.79 CA1 (0.56) CA1CA2CA7CA9CA12
SCHEMBL11420633 0.79 CA1 (0.56) CA1CA2CA7CA9CA12
SCHEMBL1377763 0.78 LMNA (0.62) HPGDKMT2AMEN1MAPK1LMNA
SCHEMBL11509883 0.77 L3MBTL1 (0.44) HPGDLMNAHTTL3MBTL1MAPT
SCHEMBL19142344 0.77 TP53 (0.61) CA1CA2CA7CA9CA12
SCHEMBL11548387 0.77 LMNA (0.43) HPGDKMT2AMAPK1LMNAHTT
SCHEMBL27453980 0.77 CA1 (0.48) CA1CA2CA7CA9CA12
SCHEMBL8016604 0.76 CA1 (0.52) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1928475-A2 ANTIVIRAL PHOSPHORAMIDATES OF 4'-SUBSTITUTED PRONUCLEOTIDES F.HOFFMANN-LA ROCHE AG (CH) 2008-06-11 EP disclosed
WO-2007020193-A2 ANTIVIRAL PHOSPHORAMIDATES OF 4 ' -SUBSTITUTED PRONUCLEOTIDES F. HOFFMANN-LA ROCHE AG (CH) 2007-02-22 WO disclosed
US-4154716-A SOLID MODIFIER, NONAMINE CATALYST THE DOW CHEMICAL COMPANY (US) 1979-05-15 US disclosed
US-4075151-A SOLID, RAPID-SETTING, RIGID POLYURETHANES THE DOW CHEMICAL COMPANY (US) 1978-02-21 US disclosed
US-4067834-A FATTY ACID OR FATTY OIL, ORGANOTIN CATALYST THE DOW CHEMICAL COMPANY (US) 1978-01-10 US disclosed
US-4060509-A Solid, rapid-setting, rigid polyurethanes THE DOW CHEMICAL COMPANY (US) 1977-11-29 US disclosed
US-4038235-A SOLID, RAPID-SETTING, RIGID POLYURETHANES THE DOW CHEMICAL COMPANY (US) 1977-07-26 US disclosed
US-4035331-A Solid, rapid-setting, rigid polyurethanes THE DOW CHEMICAL COMPANY (US) 1977-07-12 US disclosed
US-4028303-A AMINE INITIATED POLYOL, AROMATIC POLYISOCYANATE, AND A LIQUID MODIFIER THE DOW CHEMICAL COMPANY (US) 1977-06-07 US disclosed
US-4028296-A AMINE-INITIATED POLYETHER POLYOL, CATALYST-FREE, CYCLIC ETHER THE DOW CHEMICAL COMPANY (US) 1977-06-07 US disclosed
US-3983065-A Solid, rapid-setting, rigid polyurethanes THE DOW CHEMICAL COMPANY (US) 1976-09-28 US disclosed
US-3983064-A Solid, rapid-setting, rigid polyurethanes THE DOW CHEMICAL COMPANY (US) 1976-09-28 US disclosed
US-3983066-A Solid, rapid setting, rigid polyurethanes THE DOW CHEMICAL COMPANY (US) 1976-09-28 US disclosed
US-3983063-A Solid, rapid-setting, rigid polyurethanes THE DOW CHEMICAL COMPANY (US) 1976-09-28 US disclosed
US-3983069-A Solid, rapid-setting, rigid polyurethanes THE DOW CHEMICAL COMPANY (US) 1976-09-28 US disclosed
US-3983068-A Solid, rapid-setting, rigid polyurethanes THE DOW CHEMICAL COMPANY (US) 1976-09-28 US disclosed
US-3966662-A Solid, rapid-setting, rigid polyurethanes THE DOW CHEMICAL COMPANY (US) 1976-06-29 US disclosed
US-3966664-A Solid, rapid-setting, rigid polyurethanes THE DOW CHEMICAL COMPANY (US) 1976-06-29 US disclosed
US-3965073-A Preparation of rapid setting non-elastomeric polyurethane compositions in the presence of ester-modified polyoxyalkylene compounds THE DOW CHEMICAL COMPANY (US) 1976-06-22 US disclosed
US-3956221-A Rapid setting non-elastomeric polyurethane compositions containing a non-hydroxyl containing ester-modified polyoxylkylene compound THE DOW CHEMICAL COMPANY (US) 1976-05-11 US disclosed