Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 3/20 | 0.52 |
| ▸ | ANPEP | P15144 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12065590 | 0.89 | MAPK1 (0.56) | MAPK1OPRK1MCHR1MEN1KMT2A | |
| SCHEMBL15443874 | 0.86 | MCHR1 (0.53) | MAPK1OPRK1MCHR1MEN1KMT2A | |
| SCHEMBL15871566 | 0.85 | MCHR1 (0.52) | MAPK1OPRK1MCHR1MEN1KMT2A | |
| SCHEMBL3140700 | 0.82 | POLB (0.77) | MAPK1OPRK1MEN1KMT2APKM | |
| SCHEMBL409810 | 0.80 | MCHR1 (0.50) | MAPK1OPRK1MCHR1MEN1KMT2A | |
| SCHEMBL23347841 | 0.79 | MCHR1 (0.49) | MAPK1OPRK1MCHR1MEN1KMT2A | |
| SCHEMBL463415 | 0.79 | MAPK1 (0.74) | MAPK1OPRK1MCHR1MEN1KMT2A | |
| SCHEMBL12065589 | 0.78 | EPHX1 (0.55) | MAPK1OPRK1MCHR1MEN1KMT2A | |
| SCHEMBL7339569 | 0.77 | MEN1 (0.61) | MAPK1OPRK1MEN1KMT2APKM | |
| SCHEMBL11833305 | 0.76 | SIGMAR1 (0.59) | MAPK1OPRK1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065169-A1 | OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065169-A1 | OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS | NSUN2, UPF1, RTCB | MAPK1 4345/4885OPRK1 2420/4885MCHR1 4395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.