Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS12 | P56730 | 2/20 | 0.40 |
| ▸ | IL2 | P60568 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | F10 | P00742 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3616589 | 0.93 | PRSS12 (0.42) | PRSS12IL2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL3614270 | 0.89 | PRSS12 (0.44) | PRSS12ALDH1A1SMN1; SMN2F10MEN1 | |
| SCHEMBL3604203 | 0.87 | PRSS12 (0.47) | PRSS12KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL3622276 | 0.87 | PRSS12 (0.42) | PRSS12KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL3613707 | 0.86 | PRSS12 (0.43) | PRSS12KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL3615579 | 0.86 | PRSS12 (0.43) | PRSS12KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL3616979 | 0.85 | NAMPT (0.47) | KDM4ENPC1RAB9ASMN1; SMN2F10 | |
| SCHEMBL3616983 | 0.85 | F10 (0.47) | PRSS12L3MBTL1KDM4EALDH1A1NPC1 | |
| SCHEMBL3614368 | 0.85 | F10 (0.44) | PRSS12IL2KDM4EALDH1A1NPC1 | |
| SCHEMBL3617006 | 0.85 | PRSS12 (0.37) | PRSS12KDM4EALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100004292-A1 | Iminooxazolidine Derivatives and Their Use | BAYER HEALTHCARE AG (DE) | 2010-01-07 | — | — | US | disclosed |
| EP-1928868-A1 | IMINOOXAZOLIDINE DERIVATIVES AND USE THEREOF | Bayer HealthCare AG (DE) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007028520-A1 | IMINOOXAZOLIDINE DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004292-A1 | Iminooxazolidine Derivatives and Their Use | PPOX, XDH, PNPO | PRSS12 3975/4885IL2 2409/4885L3MBTL1 4730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.