SCHEMBL4634792

SCHEMBL4634792

O=[C]Oc1ccccc1-c1cc(=O)c2ccccc2o1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 8/20 0.59
CYP3A4 P08684 7/20 0.59
ALDH1A1 P00352 6/20 0.59
SMN1; SMN2 Q16637 4/20 0.59
NPC1 O15118 4/20 0.59
CYP2C19 P33261 4/20 0.59
MEN1 O00255 4/20 0.59
KMT2A Q03164 4/20 0.59
MAPT P10636 4/20 0.59
RAB9A P51151 3/20 0.59
TP53 P04637 3/20 0.59
CYP2C9 P11712 3/20 0.59
CYP2D6 P10635 2/20 0.59
ALOX15 P16050 2/20 0.59
TSHR P16473 2/20 0.59
MAPK1 P28482 2/20 0.59
GMNN O75496 1/20 0.59
RAF1 P04049 1/20 0.59
CYP1A2 P05177 1/20 0.59
PKM P14618 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21633838 0.82 HPGD (0.66) HPGDCYP3A4ALDH1A1SMN1; SMN2NPC1
SCHEMBL253522 0.82 HPGD (0.78) HPGDCYP3A4ALDH1A1SMN1; SMN2NPC1
SCHEMBL23581452 0.79 AKR1C3 (0.61) HPGDCYP3A4ALDH1A1SMN1; SMN2NPC1
SCHEMBL8038811 0.79 HPGD (0.61) HPGDCYP3A4ALDH1A1SMN1; SMN2NPC1
SCHEMBL29080547 0.79 HPGD (0.61) HPGDCYP3A4ALDH1A1SMN1; SMN2NPC1
SCHEMBL29080570 0.76 HPGD (0.57) HPGDCYP3A4ALDH1A1SMN1; SMN2NPC1
SCHEMBL4634256 0.75 HPGD (0.73) HPGDCYP3A4ALDH1A1SMN1; SMN2NPC1
SCHEMBL4649187 0.75 HPGD (0.74) HPGDCYP3A4ALDH1A1SMN1; SMN2NPC1
SCHEMBL29080528 0.75 HPGD (0.59) HPGDCYP3A4ALDH1A1SMN1; SMN2NPC1
SCHEMBL7075686 0.75 HPGD (0.56) HPGDCYP3A4ALDH1A1SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7405030-B2 Imide compound and optical recording media made by using the same MITSUI CHEMICALS, INC. (JP) 2008-07-29 US disclosed
EP-1930339-A2 Imide compound MITSUI CHEMICALS, INC. (JP) 2008-06-11 EP disclosed
US-20070259151-A1 Imide compound and optical recording media made by using the same MITSUI CHEMICALS, INC. (JP) 2007-11-08 US disclosed
US-7259260-B2 Imide compound and optical recording media made by using the same MITSUI CHEMICALS, INC. (JP) 2007-08-21 US disclosed
US-20050208425-A1 Imide compound and optical recording media made by using the same YAMAMOTO CHEMICALS, INC. (JP) 2005-09-22 US disclosed
EP-1445115-A1 IMIDE COMPOUNDS AND OPTICAL RECORDING MEDIA MADE BY USING THE SAME Mitsui Chemicals, Inc. (JP) 2004-08-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050208425-A1 Imide compound and optical recording media made by using the same CRY1, MTNR1A, TRPA1 HPGD 3323/4885CYP3A4 1620/4885ALDH1A1 1336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.