SCHEMBL4635009

SCHEMBL4635009

CC12C=CC(C1)C(CO)C2CO

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11752889 0.78
SCHEMBL4608573 0.63
SCHEMBL4633892 0.60
SCHEMBL11856419 0.58
SCHEMBL11854253 0.58
SCHEMBL5346134 0.57
SCHEMBL2832119 0.57 POLB (0.38)
SCHEMBL5351523 0.55
SCHEMBL5350398 0.55 ALDH1A1 (0.33)
SCHEMBL8348256 0.54

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7250157-B2 Dermatological compositions and methods APPLIED GENETICS INCORPORATED DERMATICS (US) 2007-07-31 US claimed
US-20060120976-A1 Dermatological compositions and methods APPLIED GENETICS INCORPORATED DERMATICS (US) 2006-06-08 US claimed
US-6955804-B2 Dermatological compositions and methods APPLIED GENETICS INCORPORATED DEMATICS (US) 2005-10-18 US claimed
US-20040067209-A1 Dermatological compositions and methods APPLIED GENETICS INCORPORATED DERMATICS 2004-04-08 US claimed
US-6623724-B2 Regulating the melanin content of mammalian melanocytes by administering alcohols, diols, triols and their analogues APPLIED GENETICS INCORPORATED DERMATICS 2003-09-23 US claimed
US-20020141952-A1 Regulating the melanin content of mammalian melanocytes by administering alcohols, diols, triols and their analogues APPLIED GENETICS INCORPORATED DERMATICS 2002-10-03 US claimed
WO-2002051395-A1 TREATMENT OF NEURODEGENERATIVE DISEASES CODON PHARMACEUTICALS, INC. (US) 2002-07-04 WO claimed
WO-1998055085-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS CODON PHARMACEUTICALS, INC. (US) 1998-12-10 WO claimed
EP-3768083-A1 PESTICIDE M H Poskitt Limited (GB) 2021-01-27 EP disclosed
US-20210007351-A1 PESTICIDE M H Poskitt Limited (GB) 2021-01-14 US disclosed
WO-2019180420-A1 PESTICIDE M H Poskitt Limited (GB) 2019-09-26 WO disclosed
EP-1757580-B1 Process for producing norbornene derivatives DAINIPPON INK & CHEMICALS (JP) 2008-06-11 EP disclosed
US-7250157-B2 Dermatological compositions and methods APPLIED GENETICS INCORPORATED DERMATICS (US) 2007-07-31 US disclosed
EP-1757580-A1 Process for producing norbornene derivatives DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-02-28 EP disclosed
US-20060120976-A1 Dermatological compositions and methods APPLIED GENETICS INCORPORATED DERMATICS (US) 2006-06-08 US disclosed
US-6955804-B2 Dermatological compositions and methods APPLIED GENETICS INCORPORATED DEMATICS (US) 2005-10-18 US disclosed
US-20040067209-A1 Dermatological compositions and methods APPLIED GENETICS INCORPORATED DERMATICS 2004-04-08 US disclosed
US-6623724-B2 Regulating the melanin content of mammalian melanocytes by administering alcohols, diols, triols and their analogues APPLIED GENETICS INCORPORATED DERMATICS 2003-09-23 US disclosed
US-20020141952-A1 Regulating the melanin content of mammalian melanocytes by administering alcohols, diols, triols and their analogues APPLIED GENETICS INCORPORATED DERMATICS 2002-10-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210007351-A1 PESTICIDE DDT, CAT, CLPP ALOX15 2196/4885
US-20020141952-A1 Regulating the melanin content of mammalian melanocytes by administering alcohols, diols, triols and their analogues TYR, MITF, MC1R ALOX15 755/4885
US-20060120976-A1 Dermatological compositions and methods TYR, MITF, ALPG ALOX15 514/4885
US-20040067209-A1 Dermatological compositions and methods TYR, MITF, ALPG ALOX15 514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.