Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27688209 | 0.87 | KMT2A (0.48) | PTPN1ALOX15L3MBTL1SMN1; SMN2POLB | |
| SCHEMBL8435546 | 0.85 | ALOX15 (0.55) | ALOX15ELANEL3MBTL1SMN1; SMN2GLA | |
| SCHEMBL26698283 | 0.85 | LMNA (0.46) | ALOX15ELANEL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL18892740 | 0.84 | KDM4E (0.54) | PTPN1L3MBTL1SMN1; SMN2POLBGLA | |
| SCHEMBL27634761 | 0.84 | PTPN1 (0.44) | PTPN1ALOX15ELANEL3MBTL1SMN1; SMN2 | |
| SCHEMBL27634751 | 0.84 | PTPN1 (0.44) | PTPN1ALOX15ELANEL3MBTL1SMN1; SMN2 | |
| SCHEMBL6249085 | 0.84 | L3MBTL1 (0.59) | ALOX15ELANEL3MBTL1POLBGLA | |
| SCHEMBL27688219 | 0.82 | PTPN1 (0.64) | PTPN1SMN1; SMN2POLBALDH1A1EGFR | |
| SCHEMBL30883175 | 0.82 | MAPT (0.57) | ALOX15ELANEL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL362210 | 0.82 | MAPT (0.57) | ALOX15ELANEL3MBTL1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105849111-B | Pyrans and the different cresol derivatives of baynide fibre and metabolic syndrome or treatment of inflammatory diseases pharmaceutical composition | 格拉斯如睦株式会社 | 2018-05-04 | — | — | CN | disclosed |
| CN-105849111-A | Pyranochromenyl phenol derivative, and pharmaceutical composition for treating metabolic syndrome or inflammatory disease | 依如睦生物科技株式会社 | 2016-08-10 | — | — | CN | disclosed |
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |