Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GPR88 | Q9GZN0 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26698292 | 0.85 | TSHR (0.45) | KMT2APTGS2PTGS1TSHRGPR88 | |
| SCHEMBL15201697 | 0.82 | KMT2A (0.53) | KMT2APTGS2PTGS1GPR88CYP2D6 | |
| SCHEMBL7651108 | 0.82 | KMT2A (0.52) | KMT2APTGS2PTGS1CYP2D6 | |
| SCHEMBL28225645 | 0.81 | ALDH1A1 (0.47) | KMT2APTGS2PTGS1TSHRGPR88 | |
| SCHEMBL3804982 | 0.80 | ALDH1A1 (0.49) | KMT2APTGS2PTGS1TSHRALDH1A1 | |
| SCHEMBL11861916 | 0.78 | KMT2A (0.48) | KMT2APTGS2PTGS1CYP1A2CYP2D6 | |
| SCHEMBL27643864 | 0.78 | GPR88 (0.49) | TSHRGPR88HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL183940 | 0.76 | KMT2A (0.67) | KMT2APTGS2PTGS1TSHRGPR88 | |
| SCHEMBL5537242 | 0.76 | KMT2A (0.67) | KMT2APTGS2PTGS1TSHRGPR88 | |
| SCHEMBL5544986 | 0.76 | KMT2A (0.67) | KMT2APTGS2PTGS1TSHRGPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |