Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4873948 | 0.77 | GPR3 (0.44) | GPR3SLC22A2SLC22A3 | |
| Hydrochloric Acid SCHEMBL4880315 | 0.67 | GPR3 (0.44) | GPR3SLC22A2SLC22A3 | |
| SCHEMBL1477602 | 0.66 | GPR3 (0.64) | GPR3SLC22A2SLC22A3HTR2A | |
| SCHEMBL7510360 | 0.65 | GPR3 (0.50) | GPR3SLC22A2SLC22A3HTR2A | |
| Hydrochloric Acid SCHEMBL4872846 | 0.63 | GPR3 (0.44) | GPR3SLC22A2SLC22A3 | |
| SCHEMBL1509312 | 0.63 | GPR3 (1.00) | GPR3SLC22A2SLC22A3HTR2A | |
| SCHEMBL28709520 | 0.61 | GPR3 (0.95) | GPR3SLC22A2SLC22A3HTR2A | |
| SCHEMBL18418388 | 0.60 | GPR3 (0.58) | GPR3SLC22A2SLC22A3 | |
| SCHEMBL1478412 | 0.60 | GPR3 (0.54) | GPR3SLC22A2SLC22A3HTR2A | |
| SCHEMBL28157515 | 0.60 | GPR3 (0.67) | GPR3SLC22A2SLC22A3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2409836-B1 | MULTILAYER PROPYLENE RESIN SHEET AND PACKAGING MATERIAL FOR HEATING TREATMENT COMPRISING SAME | JAPAN POLYPROPYLENE CORP (JP) | 2016-05-04 | — | — | EP | disclosed |
| US-8859062-B2 | Multilayer propylene resin sheet and heat-treatable packaging material using same | JAPAN POLYPROPYLENE CORPORATION (JP) | 2014-10-14 | — | — | US | disclosed |
| EP-2409836-A1 | MULTILAYER PROPYLENE RESIN SHEET AND PACKAGING MATERIAL FOR HEATING TREATMENT COMPRISING SAME | Japan Polypropylene Corporation (JP) | 2012-01-25 | — | — | EP | disclosed |
| US-20110311742-A1 | MULTILAYER PROPYLENE RESIN SHEET AND HEAT-TREATABLE PACKAGING MATERIAL USING SAME | JAPAN POLYPROPYLENE CORPORATION (JP) | 2011-12-22 | — | — | US | disclosed |
| US-20070082185-A1 | Multi-layered film | JAPAN POLYPROPYLENE CORPORATION (JP) | 2007-04-12 | — | — | US | disclosed |