Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7217277 | 0.72 | HTR2A (0.31) | — | |
| SCHEMBL7510360 | 0.72 | GPR3 (0.50) | GPR3SLC22A2SLC22A3 | |
| Hydrochloric Acid SCHEMBL4873948 | 0.70 | GPR3 (0.44) | GPR3SLC22A2SLC22A3 | |
| Hydrochloric Acid SCHEMBL4872846 | 0.70 | GPR3 (0.44) | GPR3SLC22A2SLC22A3 | |
| Hydrochloric Acid SCHEMBL9839796 | 0.69 | GPR3 (0.40) | GPR3SLC22A2SLC22A3 | |
| Hydrochloric Acid SCHEMBL673076 | 0.67 | GPR3 (0.36) | GPR3SLC22A2SLC22A3 | |
| Hydrochloric Acid SCHEMBL463546 | 0.67 | GPR3 (0.44) | GPR3SLC22A2SLC22A3 | |
| SCHEMBL1477602 | 0.66 | GPR3 (0.64) | GPR3SLC22A2SLC22A3 | |
| SCHEMBL1509312 | 0.63 | GPR3 (1.00) | GPR3SLC22A2SLC22A3 | |
| SCHEMBL7630742 | 0.62 | GPR3 (0.39) | GPR3SLC22A2SLC22A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE40234-E1 | Process for producing crystalline poly-α-olefins with a monocyclopentadienyl transition metal catalyst system | EXXONMOBIL CHEMICAL PATENTS, INC. | 2008-04-08 | — | — | US | disclosed |
| US-7041841-B1 | Process for producing crystalline poly-α-olefins with a monocyclopentadienyl transition metal catalyst system | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-05-09 | — | — | US | disclosed |
| WO-1992005204-A1 | PROCESS FOR PRODUCING CRYSTALLINE POLY-ALPHA-OLEFINS WITH A MONOCYCLOPENTADIENYL TRANSITION METAL CATALYST SYSTEM | EXXON CHEMICAL PATENTS INC. (US) | 1992-04-02 | — | — | WO | disclosed |
| US-5026798-A | Coordination catalyst | EXXON CHEMICAL PATENTS INC. (US) | 1991-06-25 | — | — | US | disclosed |