Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 2/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7630742 | 0.84 | GPR3 (0.39) | GPR3SLC22A2SLC22A3 | |
| SCHEMBL4375149 | 0.80 | GPR3 (0.36) | GPR3SLC22A2SLC22A3 | |
| SCHEMBL7629468 | 0.74 | GPR3 (0.32) | GPR3 | |
| Hydrochloric Acid SCHEMBL4873948 | 0.72 | GPR3 (0.44) | GPR3SLC22A2SLC22A3 | |
| Hydrochloric Acid SCHEMBL4880315 | 0.72 | GPR3 (0.44) | GPR3SLC22A2SLC22A3 | |
| Hydrochloric Acid SCHEMBL4872846 | 0.72 | GPR3 (0.44) | GPR3SLC22A2SLC22A3 | |
| SCHEMBL1477602 | 0.71 | GPR3 (0.64) | GPR3SLC22A2SLC22A3KMT2AHTR2A | |
| SCHEMBL7634050 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL673076 | 0.68 | GPR3 (0.36) | GPR3SLC22A2SLC22A3 | |
| SCHEMBL1509312 | 0.68 | GPR3 (1.00) | GPR3SLC22A2SLC22A3KMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070072-A4 | SILYLATED AND N-SILYLATED COMPOUND SYNTHESIS | BOULDER SCIENT CO (US) | 2002-09-25 | — | — | EP | disclosed |
| EP-1150986-A4 | SILYL AMINES | BOULDER SCIENT CO (US) | 2002-08-07 | — | — | EP | disclosed |
| US-6410767-B2 | USING N-SILYLATED MONO(CYCLOPENTADIENYL) LIGAND | BOULDER SCIENTIFIC CO. | 2002-06-25 | — | — | US | disclosed |
| US-20010056199-A1 | Silylated and N-silylated compound synthesis | BOULDER SCIENTIFIC COMPANY | 2001-12-27 | — | — | US | disclosed |
| EP-1150986-A1 | SILYL AMINES | BOULDER SCIENTIFIC COMPANY (US) | 2001-11-07 | — | — | EP | disclosed |
| WO-2001038334-A1 | SILYL AMINES | BOULDER SCIENTIFIC COMPANY (US) | 2001-05-31 | — | — | WO | disclosed |
| US-6180810-B1 | SILYL AMINES WHICH BOND COVALENTLY TO METAL CENTER OF COMPLEX TO PROVIDE OLEFIN POLYMERIZATION CATALYST COMPONENT | BOULDER SCIENTIFIC COMPANY | 2001-01-30 | — | — | US | disclosed |
| EP-1070072-A1 | SILYLATED AND N-SILYLATED COMPOUND SYNTHESIS | BOULDER SCIENTIFIC COMPANY (US) | 2001-01-24 | — | — | EP | disclosed |
| WO-2000047587-A1 | SILYLATED AND N-SILYLATED COMPOUND SYNTHESIS | BOULDER SCIENTIFIC COMPANY (US) | 2000-08-17 | — | — | WO | disclosed |
| US-6087518-A | Silylated and N-silylated compound synthesis | BOULDER SCIENTIFIC COMPANY (US) | 2000-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010056199-A1 | Silylated and N-silylated compound synthesis | LSS, NCL, FNTA | GPR3 2349/4885SLC22A2 4192/4885SLC22A3 4249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.