Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634621 | 1.00 | NOTUM (0.41) | NOTUMKDM4EPOLBMAPTTHRB | |
| SCHEMBL9628149 | 0.77 | CYP3A4 (0.50) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL4634857 | 0.71 | NOTUM (0.42) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL4634569 | 0.70 | MAPT (0.54) | KDM4EPOLBMAPTTHRBRECQL | |
| SCHEMBL4634570 | 0.70 | MAPT (0.54) | KDM4EPOLBMAPTTHRBRECQL | |
| SCHEMBL8513191 | 0.67 | NOTUM (0.37) | NOTUMCYP3A4 | |
| SCHEMBL9344674 | 0.67 | NOTUM (0.38) | NOTUM | |
| SCHEMBL7878066 | 0.67 | NOTUM (0.57) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL9628331 | 0.66 | ALDH1A1 (0.45) | NOTUMKDM4EPOLBMAPTTHRB | |
| SCHEMBL15850522 | 0.64 | PDE2A (0.41) | NOTUMKDM4EPOLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1524261-B1 | Process for preparing fluorinated anilines | SALTIGO GMBH (DE) | 2008-06-11 | — | — | EP | claimed |
| US-7154006-B2 | Preparation of fluorinated anilines | BAYER AKTIENGESELLSCHAFT (DE) | 2006-12-26 | — | — | US | claimed |
| US-20050101795-A1 | Preparation of fluorinated anilines | BAYER CHEMICALS AG | 2005-05-12 | — | — | US | claimed |
| US-7154006-B2 | Preparation of fluorinated anilines | BAYER AKTIENGESELLSCHAFT (DE) | 2006-12-26 | — | — | US | disclosed |
| US-20050101795-A1 | Preparation of fluorinated anilines | BAYER CHEMICALS AG | 2005-05-12 | — | — | US | disclosed |
| EP-1524261-A1 | Process for preparing fluorinated anilines | Bayer Chemicals AG (DE) | 2005-04-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101795-A1 | Preparation of fluorinated anilines | FLNA, FLNB, FLI1 | NOTUM 197/4885KDM4E 2215/4885POLB 528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.