Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | SSTR5 | P35346 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | EED | O75530 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MLNR | O43193 | 1/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | HLA-A | P04439 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9564852 | 0.86 | KCNH2 (0.57) | KCNH2NR4A2SSTR5LMNAGAA | |
| SCHEMBL4635524 | 0.80 | SSTR5 (0.44) | KCNH2NR4A2SSTR5LMNAGAA | |
| SCHEMBL9564827 | 0.79 | SSTR5 (0.44) | KCNH2NR4A2SSTR5LMNAGAA | |
| SCHEMBL9564865 | 0.77 | SSTR5 (0.63) | KCNH2NR4A2SSTR5LMNAGAA | |
| SCHEMBL9564786 | 0.76 | ALDH1A1 (0.47) | LMNAGAAMEN1MAPTHTT | |
| SCHEMBL10529762 | 0.74 | SSTR5 (0.78) | KCNH2NR4A2SSTR5LMNAGAA | |
| SCHEMBL11480609 | 0.73 | SSTR5 (0.57) | KCNH2NR4A2SSTR5LMNAGAA | |
| SCHEMBL10057014 | 0.72 | P2RX3 (0.56) | KCNH2NR4A2SSTR5LMNAGAA | |
| SCHEMBL9564765 | 0.72 | KCNH2 (0.58) | KCNH2NR4A2SSTR5LMNAGAA | |
| SCHEMBL9631566 | 0.72 | CYP1A2 (0.50) | KCNH2NR4A2SSTR5LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258380-A | Antiallergens, antihistamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-11-02 | — | — | US | disclosed |
| US-5041448-A | Antiallergens | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-08-20 | — | — | US | disclosed |
| EP-0206415-A2 | (4-Piperidinylmethyl and -hetero)purines | JANSSEN PHARMACEUTICA N.V. (BE) | 1986-12-30 | — | — | EP | disclosed |