SCHEMBL5428987

SCHEMBL5428987

COC(=O)c1cc(N)ccc1O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SNCA P37840 1/20 0.57
ACHE P22303 1/20 0.53
APP P05067 1/20 0.52
PTGS1 P23219 1/20 0.51
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
SLC28A3 Q9HAS3 1/20 0.49
DYRK1A Q13627 1/20 0.48
KDM4E B2RXH2 1/20 0.48
POLB P06746 1/20 0.48
GAA P10253 1/20 0.48
RECQL P46063 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5435886 1.00 SNCA (0.57) SNCAACHEAPPPTGS1MEN1
SCHEMBL5431937 1.00 SNCA (0.57) SNCAACHEAPPPTGS1MEN1
SCHEMBL4635652 0.87 SNCA (0.58) SNCAACHEAPPPTGS1SLC28A3
SCHEMBL5427804 0.87 ACHE (0.50) SNCAACHEMEN1KMT2ASLC28A3
SCHEMBL5427382 0.87 ACHE (0.50) SNCAACHEMEN1KMT2ASLC28A3
SCHEMBL5437894 0.87 ACHE (0.50) SNCAACHEMEN1KMT2ASLC28A3
SCHEMBL17873961 0.87 ACHE (0.50) SNCAACHEMEN1KMT2ASLC28A3
SCHEMBL5429570 0.82 CYP1A2 (0.58) SNCAACHEAPPPTGS1
SCHEMBL4635920 0.80 SLC28A3 (0.58) SNCAAPPSLC28A3KDM4E
SCHEMBL27932802 0.80 SLC28A3 (0.49) SNCAACHESLC28A3GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070173461-A1 Glycoside prodrug of 5- aminosalicylic acid NIPPON SHINYAKU CO., LTD. (JP) 2007-07-26 US disclosed
EP-1712555-A1 PRODRUG COMPRISING 5-AMINOSALICYLATE GLYCOSIDE Nippon Shinyaku Co., Ltd. (JP) 2006-10-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070173461-A1 Glycoside prodrug of 5- aminosalicylic acid SI, FUT5, GALE SNCA 3714/4885ACHE 1092/4885APP 3611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.