Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 11/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 3/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4636792 | 0.90 | CYP11B1 (0.35) | P2RX7CYP11B1CYP11B2CTSSDHODH | |
| SCHEMBL4145038 | 0.87 | ATM (0.35) | — | |
| SCHEMBL4155015 | 0.86 | TLR7 (0.40) | — | |
| SCHEMBL4636710 | 0.86 | CYP11B1 (0.33) | P2RX7CYP11B1CYP11B2CTSSDHODH | |
| SCHEMBL4636118 | 0.85 | CES2 (0.33) | CTSSDHODH | |
| SCHEMBL4637596 | 0.83 | TAS1R3 (0.38) | P2RX7CTSSDHODH | |
| SCHEMBL4150885 | 0.83 | MEN1 (0.39) | — | |
| SCHEMBL4636197 | 0.82 | ALDH2 (0.34) | P2RX7CYP11B1CYP11B2CTSSDHODH | |
| SCHEMBL4158482 | 0.81 | MEN1 (0.39) | DHODH | |
| SCHEMBL4637507 | 0.80 | RXFP1 (0.35) | CTSSGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937629-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007046513-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-26 | — | — | WO | disclosed |