Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | PPIA | P62937 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4157453 | 0.86 | TRPA1 (0.36) | RAB9APPIAPOLBRORC | |
| SCHEMBL4636792 | 0.85 | CYP11B1 (0.35) | ALDH2P2RX7CYP11B1CYP11B2DHODH | |
| SCHEMBL4154465 | 0.85 | RORC (0.41) | RAB9APPIAPOLBRORCLMNA | |
| SCHEMBL4636352 | 0.82 | P2RX7 (0.33) | ALDH2P2RX7CYP11B1CYP11B2DHODH | |
| SCHEMBL4636710 | 0.82 | CYP11B1 (0.33) | ALDH2P2RX7CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL4636733 | 0.78 | CES2 (0.33) | P2RX7DHODHCTSS | |
| SCHEMBL4637596 | 0.78 | TAS1R3 (0.38) | TAS1R3TAS1R1TAS1R2P2RX7DHODH | |
| SCHEMBL4637621 | 0.78 | CES2 (0.32) | — | |
| SCHEMBL4637507 | 0.74 | RXFP1 (0.35) | ALDH1A1CTSSLMNA | |
| SCHEMBL4160195 | 0.74 | TRPA1 (0.35) | ALDH1A1RAB9APOLBRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937629-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007046513-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-26 | — | — | WO | disclosed |