Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.34 |
| ▸ | STARD10 | Q9Y365 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.34 |
| ▸ | F2R | P25116 | 1/20 | 0.34 |
| ▸ | KCNK2 | O95069 | 3/20 | 0.33 |
| ▸ | KCNK10 | P57789 | 3/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4636792 | 0.93 | CYP11B1 (0.35) | P2RX7RXFP1KCNK2KCNK10DHODH | |
| SCHEMBL4149982 | 0.89 | RORC (0.38) | RORC | |
| SCHEMBL4154004 | 0.87 | TLR7 (0.42) | RORC | |
| SCHEMBL4637507 | 0.86 | RXFP1 (0.35) | RXFP1KCNK2KCNK10CTSS | |
| SCHEMBL5425678 | 0.85 | P2RX7 (0.38) | TAS1R3TAS1R1TAS1R2TMEM97SIGMAR1 | |
| SCHEMBL4636352 | 0.83 | P2RX7 (0.33) | P2RX7DHODHCTSS | |
| SCHEMBL4636710 | 0.83 | CYP11B1 (0.33) | P2RX7DHODHCTSS | |
| SCHEMBL4158996 | 0.83 | TRPA1 (0.34) | RXFP1KCNK2KCNK10RORC | |
| SCHEMBL4150976 | 0.81 | MEN1 (0.39) | RORC | |
| SCHEMBL4637632 | 0.78 | CES2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937629-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007046513-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-26 | — | — | WO | disclosed |